Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10441856 | 1.00 | SIGMAR1 (0.45) | SIGMAR1ESR2GAASCN5ASCN9A | |
| SCHEMBL28803638 | 1.00 | SIGMAR1 (0.45) | SIGMAR1ESR2GAASCN5ASCN9A | |
| SCHEMBL28001899 | 1.00 | SIGMAR1 (0.45) | SIGMAR1ESR2GAASCN5ASCN9A | |
| SCHEMBL27299341 | 1.00 | SIGMAR1 (0.45) | SIGMAR1ESR2GAASCN5ASCN9A | |
| SCHEMBL500650 | 1.00 | SIGMAR1 (0.45) | SIGMAR1ESR2GAASCN5ASCN9A | |
| SCHEMBL1581793 | 1.00 | SIGMAR1 (0.45) | SIGMAR1ESR2GAASCN5ASCN9A | |
| SCHEMBL10441612 | 0.98 | SIGMAR1 (0.46) | SIGMAR1ESR2GAASCN5ASCN9A | |
| SCHEMBL845807 | 0.92 | ESR2 (0.47) | SIGMAR1ESR2CYP2C19 | |
| SCHEMBL3190448 | 0.90 | SIGMAR1 (0.47) | SIGMAR1ESR2CYP2C19 | |
| SCHEMBL3200007 | 0.86 | CYP2C19 (0.50) | SIGMAR1ESR2KMT2ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10175589-B2 | Quinone derivative and electrophotographic photosensitive member | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2019-01-08 | — | — | US | disclosed |
| US-20170363978-A1 | QUINONE DERIVATIVE AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2017-12-21 | — | — | US | disclosed |
| US-20170363978-A1 | QUINONE DERIVATIVE AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2017-12-21 | — | — | US | disclosed |
| WO-2003031625-A1 | ESTERASE ESTA EXTRACTED FROM RHODOCOCCUS RUBER | DEGUSSA AG (DE) | 2003-04-17 | — | — | WO | disclosed |
| WO-2003031609-A1 | ESTERASE ESTA OF RHODOCOCCUS SP. | DEGUSSA AG (DE) | 2003-04-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10175589-B2 | Quinone derivative and electrophotographic photosensitive member | KEAP1, NQO1, CBR3 | SIGMAR1 2923/4885ESR2 1121/4885GAA 1955/4885 |
| US-20170363978-A1 | QUINONE DERIVATIVE AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | KEAP1, NQO1, CBR3 | SIGMAR1 2923/4885ESR2 1121/4885GAA 1955/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.