SCHEMBL7157284

SCHEMBL7157284

O=C(Cn1c(-c2cccc(Cl)c2)ncc(NC(=O)OCc2ccccc2)c1=O)NC(Cc1ccccc1)C(=O)C(F)(F)C(=O)NCc1ccccc1

nearest known ligand 0.74

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CMA1 P23946 12/20 0.74
CTRC Q99895 12/20 0.74
CTSG P08311 1/20 0.74
ELANE P08246 8/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6557710 0.91 CMA1 (0.74) CMA1CTRCCTSGELANE
SCHEMBL6557714 0.91 CMA1 (0.74) CMA1CTRCCTSGELANE
SCHEMBL7156660 0.89 ELANE (0.60) CMA1CTRCCTSGELANE
SCHEMBL6558307 0.87 ELANE (0.79) CMA1CTRCELANE
SCHEMBL6557712 0.87 ELANE (0.79) CMA1CTRCELANE
SCHEMBL6558089 0.85 CTRC (0.73) CMA1CTRCELANE
SCHEMBL6558085 0.85 CTRC (0.73) CMA1CTRCELANE
SCHEMBL7151817 0.85 CTRC (1.00) CMA1CTRCCTSG
SCHEMBL6558274 0.85 ELANE (0.77) CMA1CTRCELANE
SCHEMBL6556244 0.83 CTRC (0.77) CMA1CTRCELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6528514-B1 Pyrimidin-4-one-5-amino-3-alkylcarboxamidomethyl compounds WELFIDE CORPORATION (JP) 2003-03-04 US disclosed
EP-1062949-A1 IgE ANTIBODY PRODUCTION INHIBITORS AND AUTOIMMUNE DISEASES INHIBITORS Welfide Corporation (JP) 2000-12-27 EP disclosed