Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | MLYCD | O95822 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8605252 | 0.82 | POLB (0.60) | POLBHTTTACR1MLYCDSMN1; SMN2 | |
| Dimorpholamine SCHEMBL34539 | 0.80 | POLB (0.58) | POLBHTTTACR1MLYCDSMN1; SMN2 | |
| Dimorpholamine SCHEMBL2689742 | 0.79 | POLB (0.57) | POLBHTTTACR1MLYCDSMN1; SMN2 | |
| SCHEMBL8014785 | 0.77 | TACR1 (0.65) | POLBTACR1 | |
| SCHEMBL2418238 | 0.77 | SMN1; SMN2 (0.56) | POLBHTTSMN1; SMN2LMNARAB9A | |
| SCHEMBL12472375 | 0.75 | POLB (0.64) | POLBHTTMLYCDSMN1; SMN2LMNA | |
| SCHEMBL29206561 | 0.75 | MLYCD (0.50) | POLBHTTTACR1MLYCDSMN1; SMN2 | |
| SCHEMBL11553402 | 0.73 | L3MBTL1 (0.65) | POLBHTTSMN1; SMN2LMNAMEN1 | |
| SCHEMBL17498262 | 0.73 | L3MBTL1 (0.65) | POLBHTTSMN1; SMN2LMNAMEN1 | |
| SCHEMBL3742384 | 0.72 | HTT (0.50) | POLBHTTSMN1; SMN2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8571659-B2 | Implantable medical device with chemical sensor and related methods | CARDIAC PACEMAKERS, INC. (US) | 2013-10-29 | — | — | US | disclosed |
| US-20120197231-A1 | IMPLANTABLE MEDICAL DEVICE WITH CHEMICAL SENSOR AND RELATED METHODS | CARDIAC PACEMAKERS, INC (US) | 2012-08-02 | — | — | US | disclosed |
| US-8126554-B2 | Implantable medical device with chemical sensor and related methods | CARDIAC PACEMAKERS, INC. (US) | 2012-02-28 | — | — | US | disclosed |
| US-7809441-B2 | Implantable medical device with chemical sensor and related methods | CARDIAC PACEMAKERS, INC. (US) | 2010-10-05 | — | — | US | disclosed |
| EP-2024024-A1 | IMPLANTABLE MEDICAL DEVICE WITH CHEMICAL SENSOR AND RELATED METHODS | Cardiac Pacemakers, Inc. (US) | 2009-02-18 | — | — | EP | disclosed |
| WO-2007137037-A1 | IMPLANTABLE MEDICAL DEVICE WITH CHEMICAL SENSOR AND RELATED METHODS | CARDIAC PACEMAKERS, INC. (US) | 2007-11-29 | — | — | WO | disclosed |
| US-20070270674-A1 | Implantable Medical Device with Chemical Sensor and Related Methods | CARDIAC PACEMAKERS, INC. | 2007-11-22 | — | — | US | disclosed |
| US-20070270675-A1 | Implantable Medical Device with Chemical Sensor and Related Methods | CARDIAC PACEMAKERS, INC. | 2007-11-22 | — | — | US | disclosed |