Dimorpholamine

Dimorpholamine

SCHEMBL34539

CCCCN(CCN(CCCC)C(=O)N1CCOCC1)C(=O)N1CCOCC1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.58
HTT P42858 3/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
LMNA P02545 1/20 0.49
MLYCD O95822 6/20 0.48
TACR1 P25103 1/20 0.48
MAPT P10636 1/20 0.46
HPGD P15428 1/20 0.44
TSHR P16473 1/20 0.43
PKM P14618 1/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimorpholamine SCHEMBL2689742 0.98 POLB (0.57) POLBHTTSMN1; SMN2LMNAMLYCD
SCHEMBL8605252 0.98 POLB (0.60) POLBHTTSMN1; SMN2LMNAMLYCD
SCHEMBL12472375 0.87 POLB (0.64) POLBHTTSMN1; SMN2LMNAMLYCD
SCHEMBL9469495 0.85 POLB (0.50) POLBHTTSMN1; SMN2LMNAMLYCD
SCHEMBL8605240 0.83 POLB (0.50) POLBHTTSMN1; SMN2LMNAMLYCD
SCHEMBL715792 0.80 POLB (0.46) POLBHTTSMN1; SMN2LMNAMLYCD
SCHEMBL14229118 0.80 L3MBTL1 (0.52) TACR1HPGDMEN1KMT2A
SCHEMBL12086329 0.80 POLB (0.86) POLBHTTSMN1; SMN2LMNAMLYCD
SCHEMBL11506406 0.79 HTR1A (0.67) POLBLMNATACR1MAPTTSHR
SCHEMBL8014785 0.78 TACR1 (0.65) POLBTACR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 611 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119033774-A KL1333 composition and application thereof in preparation of tumor treatment drugs 澳门大学 2024-11-29 CN claimed
CN-114264622-B NO based on satellite-borne hyperspectral remote sensing technology2Method and device for quick response of concentration 中国科学院合肥物质科学研究院 2024-07-23 CN claimed
CN-118222607-A Soybean immunity negative regulation gene 6-phosphate trehalose synthase GmTPS, encoding protein and application thereof 上海师范大学 2024-06-21 CN claimed
CN-117904013-A Coli plasmid using steroid compound to induce resistance gene expression and application thereof 中国科学院天津工业生物技术研究所 2024-04-19 CN claimed
WO-2023246464-A1 USE OF CRYPTOTANSHINONE SUBSTANCE AND COMBINED COMPOSITION THEREOF 澳门大学 2023-12-28 WO claimed
CN-116286702-A Asparagus dehydrogenase mutant and application thereof 鲁东大学 2023-06-23 CN claimed
CN-114264622-A NO based on satellite-borne hyperspectral remote sensing technology2Method and device for quick response of concentration 中国科学院合肥物质科学研究院 2022-04-01 CN claimed
CN-109880835-B Recombinant H9N2 avian influenza virus strain, preparation method thereof, avian influenza vaccine and application thereof 扬州大学 2022-03-25 CN claimed
US-20200397702-A1 PHARMACEUTICAL COMPOSITIONS SHIN NIPPON BIOMEDICAL LABORATORIES, LTD. (JP) 2020-12-24 US claimed
US-20200147076-A1 PARENTERAL FORMULATIONS OF LIPOPHILIC PHARMACEUTICAL AGENTS AND METHODS FOR PREPARING AND USING THE SAME PLATFORM BRIGHTWORKS TWO, LTD. (US) 2020-05-14 US claimed
WO-2012148799-A1 IMPROVED PARENTERAL FORMULATIONS OF LIPOPHILIC PHARMACEUTICAL AGENTS AND METHODS FOR PREPARING AND USING THE SAME BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2012-11-01 WO claimed
US-20080260848-A1 Compositions that Enable Rapid-Acting and Highly Absorptive Intranasal Administration TRANSLATIONAL RESEARCH, LTD., (JP) 2008-10-23 US claimed
EP-1981502-A2 PHARMACEUTICAL COMPOSITION CONTAINING A CENTRAL OPIOID AGONIST, A CENTRAL OPIOID ANTAGONIST, AND A PERIPHERAL OPIOID ANTAGONIST, AND METHOD FOR MAKING THE SAME Harrogate Holdings (BM) 2008-10-22 EP claimed
WO-2007088489-A2 PHARMACEUTICAL COMPOSITION CONTAINING A CENTRAL OPIOID AGONIST, A CENTRAL OPIOID ANTAGONIST, AND A PERIPHERAL OPIOID ANTAGONIST, AND METHOD FOR MAKING THE SAME HARROGATE HOLDINGS (US) 2007-08-09 WO claimed
US-20070185145-A1 Pharmaceutical composition containing a central opioid agonist, a central opioid antagonist, and a peripheral opioid antagonist, and method for making the same HARROGATE HOLDINGS (BM) 2007-08-09 US claimed
EP-1785145-A1 TRANSNASAL COMPOSITION HAVING IMMEDIATE ACTION AND HIGH ABSORBABILITY Translational Research, Ltd. (JP) 2007-05-16 EP claimed
CN-1294519-A Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient INPHARMA SA (CH) 2001-05-09 CN claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
US-5811547-A Method for inducing crystalline state transition in medicinal substance NIPPON SHINYAJU CO., LTD. (JP) 1998-09-22 US claimed