Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16661155 | 0.90 | DGAT1 (0.46) | TSHRSLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL12748512 | 0.87 | ALDH1A1 (0.52) | TSHRSLC6A2SLC6A4SLC6A3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1474973 | 0.86 | ALDH1A1 (0.51) | TSHRSLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL12748509 | 0.84 | LMNA (0.51) | SLC6A2SLC6A4SLC6A3ALDH1A1HTR3A | |
| Hydrochloric Acid SCHEMBL1475166 | 0.83 | LMNA (0.50) | SLC6A2SLC6A4SLC6A3ALDH1A1HTR3A | |
| SCHEMBL16759161 | 0.82 | ALDH1A1 (0.50) | SLC6A2SLC6A4SLC6A3ALDH1A1CHRM2 | |
| SCHEMBL1474965 | 0.81 | IRAK4 (0.51) | SLC6A2SLC6A4SLC6A3ALDH1A1CHRM2 | |
| Hydrochloric Acid SCHEMBL16759698 | 0.80 | IRAK4 (0.50) | SLC6A2SLC6A4SLC6A3ALDH1A1CHRM2 | |
| SCHEMBL27599474 | 0.80 | ALDH1A1 (0.50) | TSHRSLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL28754655 | 0.79 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3ALDH1A1HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1328514-A1 | AMIDE DERIVATIVES AS NMDA RECEPTOR ANTAGONISTS | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 2003-07-23 | — | — | EP | disclosed |
| WO-2002034718-A1 | AMIDE DERIVATIVES AS NMDA RECEPTOR ANTAGONISTS | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2002-05-02 | — | — | WO | disclosed |