Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 3/20 | 0.49 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7160855 | 0.83 | MEN1 (0.47) | PRMT5WDR77ALDH1A1KCNJ1KCNH2 | |
| SCHEMBL17986158 | 0.81 | KCNJ1 (0.51) | SIGMAR1KDM4EKCNJ1KCNH2TDP1 | |
| SCHEMBL8930758 | 0.79 | SIGMAR1 (0.51) | SIGMAR1KDM4EALDH1A1KCNJ1KCNH2 | |
| SCHEMBL7158054 | 0.79 | DRD4 (0.46) | PRMT5WDR77KDM4EALDH1A1KCNH2 | |
| SCHEMBL7159442 | 0.79 | PRMT5 (0.47) | PRMT5WDR77OPRD1ALDH1A1 | |
| SCHEMBL15709381 | 0.76 | KDM4E (0.47) | OPRM1OPRD1SIGMAR1KDM4EALDH1A1 | |
| SCHEMBL7157651 | 0.75 | TDP1 (0.69) | KDM4EALDH1A1LMNATDP1L3MBTL1 | |
| SCHEMBL4582800 | 0.75 | TSHR (0.53) | KDM4EALDH1A1KCNJ1KCNH2LMNA | |
| SCHEMBL16364782 | 0.75 | TSHR (0.53) | KDM4EALDH1A1KCNJ1KCNH2LMNA | |
| SCHEMBL9610816 | 0.74 | KDM4E (0.65) | KDM4EALDH1A1KCNJ1LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0768898-B1 | CASCADE-POLYMER COMPLEXES AND METHODS OF PRODUCING THE SAME | SCHERING AG (DE) | 2003-04-09 | — | — | EP | disclosed |
| US-6248306-B1 | MEDICAL DIAGNOSIS | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-06-19 | — | — | US | disclosed |
| EP-0768898-A1 | CASCADE-POLYMER COMPLEXES AND METHODS OF PRODUCING THE SAME | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-04-23 | — | — | EP | disclosed |
| WO-1996001655-A1 | CASCADE-POLYMER COMPLEXES AND METHODS OF PRODUCING THE SAME | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-01-25 | — | — | WO | disclosed |