Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8930591 | 0.82 | SIGMAR1 (0.48) | SIGMAR1ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL8034304 | 0.80 | KDM4E (0.65) | ALDH1A1KDM4EKCNJ1LMNAL3MBTL1 | |
| SCHEMBL9610816 | 0.80 | KDM4E (0.65) | ALDH1A1KDM4EKCNJ1LMNAL3MBTL1 | |
| SCHEMBL7158186 | 0.79 | PRMT5 (0.49) | SIGMAR1ALDH1A1KDM4EKCNJ1KCNH2 | |
| SCHEMBL8509511 | 0.78 | KCNJ1 (0.77) | SIGMAR1KCNJ1KCNH2 | |
| SCHEMBL8715859 | 0.78 | KCNJ1 (0.77) | SIGMAR1KCNJ1KCNH2 | |
| SCHEMBL4582800 | 0.78 | TSHR (0.53) | ALDH1A1KDM4EKCNJ1KCNH2LMNA | |
| SCHEMBL16364782 | 0.78 | TSHR (0.53) | ALDH1A1KDM4EKCNJ1KCNH2LMNA | |
| SCHEMBL9612255 | 0.77 | CA2 (0.51) | ALDH1A1KDM4ELMNAHTTL3MBTL1 | |
| SCHEMBL15709381 | 0.77 | KDM4E (0.47) | SIGMAR1ALDH1A1KDM4EKCNJ1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997014443-A1 | MAGNETICALLY LABELED CHEMOATTRACTANTS AS TARGETED CONTRAST AGENTS IN THE NMR IMAGING OF LIVING TISSUES | BRACCO INTERNATIONAL B.V. (NL) | 1997-04-24 | — | — | WO | disclosed |