SCHEMBL7158486

SCHEMBL7158486

Nn1nnc2c1CCCCCCCC2

nearest known ligand 0.32

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
APAF1 O14727 1/20 0.32
NSD2 O96028 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TP53 P04637 1/20 0.32
MAPT P10636 1/20 0.32
CASP3 P42574 1/20 0.32
SENP8 Q96LD8 1/20 0.32
SENP7 Q9BQF6 1/20 0.32
SENP6 Q9GZR1 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11615448 0.83
SCHEMBL24438544 0.74 POLB (0.36) ALDH1A1MAPTTDP1L3MBTL1
SCHEMBL14963603 0.74 POLB (0.36) ALDH1A1MAPTTDP1L3MBTL1
SCHEMBL24438561 0.74 POLB (0.36) ALDH1A1MAPTTDP1L3MBTL1
SCHEMBL13415330 0.74 POLB (0.36) ALDH1A1MAPTTDP1L3MBTL1
SCHEMBL20960388 0.73
SCHEMBL13415345 0.71 POLB (0.38) KDM4EAPAF1NSD2ALDH1A1TP53
SCHEMBL9858158 0.70 PKM (0.31) KDM4E
SCHEMBL24149575 0.70
SCHEMBL24149574 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0964028-B1 Silica reinforced tire compositions containing triazoles PIRELLI (IT) 2003-10-29 EP claimed
JP-2000026661-A SILICA-REINFORCED COMPOSITION FOR TIRE PIRELLI PNEUMATICI SPA 2000-01-25 JP disclosed