Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
| ▸ | HPN | P05981 | 2/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20595935 | 0.96 | NPSR1 (0.50) | NPSR1ALDH1A1HTTKMT2ALMNA | |
| SCHEMBL20595936 | 0.96 | NPSR1 (0.50) | NPSR1ALDH1A1HTTKMT2ALMNA | |
| SCHEMBL7521944 | 0.95 | NPSR1 (0.52) | NPSR1ALDH1A1HTTKMT2ALMNA | |
| SCHEMBL177000 | 0.95 | NPSR1 (0.52) | NPSR1ALDH1A1HTTKMT2ALMNA | |
| SCHEMBL4859034 | 0.95 | NPSR1 (0.52) | NPSR1ALDH1A1HTTKMT2ALMNA | |
| SCHEMBL7092708 | 0.94 | NPSR1 (0.51) | NPSR1ALDH1A1HTTKMT2ALMNA | |
| Hydrochloric Acid SCHEMBL19716224 | 0.94 | NPSR1 (0.51) | NPSR1ALDH1A1HTTKMT2ALMNA | |
| SCHEMBL2840439 | 0.94 | NPSR1 (0.51) | NPSR1ALDH1A1HTTKMT2ALMNA | |
| SCHEMBL2844278 | 0.94 | NPSR1 (0.51) | NPSR1ALDH1A1HTTKMT2ALMNA | |
| SCHEMBL258422 | 0.92 | ALDH1A1 (0.53) | NPSR1ALDH1A1HTTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6545188-B2 | Catalytic hydrogenation a acetophenone compound or corresponding imine compound | AVECIA LIMITED (GB) | 2003-04-08 | — | — | US | disclosed |
| US-20020156282-A1 | Transfer hydrogenation process and catalyst | AVECIA LIMITED | 2002-10-24 | — | — | US | disclosed |
| EP-0971865-B1 | TRANSFER HYDROGENATION PROCESS AND CATALYST | AVECIA LTD (GB) | 2002-08-14 | — | — | EP | disclosed |
| US-6372931-B1 | CATALYST COMPRISING COMPLEX OF TRANSITION METAL, CHELATING LIGAND AND CYCLOPENTADIENYL GROUP | AVECIA LIMITED (GB) | 2002-04-16 | — | — | US | disclosed |
| EP-0971865-A1 | TRANSFER HYDROGENATION PROCESS AND CATALYST | Avecia Limited (GB) | 2000-01-19 | — | — | EP | disclosed |
| WO-1998042643-A1 | TRANSFER HYDROGENATION PROCESS AND CATALYST | AVECIA LIMITED (GB) | 1998-10-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020156282-A1 | Transfer hydrogenation process and catalyst | HRH3, HRH4, HRH1 | NPSR1 2147/4885ALDH1A1 1121/4885HTT 512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.