Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | HPN | P05981 | 2/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7521944 | 1.00 | NPSR1 (0.52) | NPSR1ALDH1A1HTTSLC1A3SLC1A2 | |
| SCHEMBL4859034 | 1.00 | NPSR1 (0.52) | NPSR1ALDH1A1HTTSLC1A3SLC1A2 | |
| SCHEMBL7092708 | 0.96 | NPSR1 (0.51) | NPSR1ALDH1A1HTTSLC1A3SLC1A2 | |
| SCHEMBL2840439 | 0.96 | NPSR1 (0.51) | NPSR1ALDH1A1HTTSLC1A3SLC1A2 | |
| Hydrochloric Acid SCHEMBL19716224 | 0.96 | NPSR1 (0.51) | NPSR1ALDH1A1HTTSLC1A3SLC1A2 | |
| SCHEMBL2844278 | 0.96 | NPSR1 (0.51) | NPSR1ALDH1A1HTTSLC1A3SLC1A2 | |
| P-Xylene SCHEMBL5424500 | 0.96 | ALDH1A1 (0.52) | NPSR1ALDH1A1HTTSLC1A3SLC1A2 | |
| SCHEMBL28382647 | 0.96 | ALDH1A1 (0.52) | NPSR1ALDH1A1HTTSLC1A3SLC1A2 | |
| SCHEMBL3342411 | 0.96 | ALDH1A1 (0.52) | NPSR1ALDH1A1HTTSLC1A3SLC1A2 | |
| P-Xylene SCHEMBL5421492 | 0.96 | ALDH1A1 (0.52) | NPSR1ALDH1A1HTTSLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9181217-B2 | Method for producing optically active naphthalene compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2015-11-10 | — | — | US | disclosed |
| US-20150152082-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE NAPHTHALENE COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2015-06-04 | — | — | US | disclosed |
| US-8304443-B2 | Indazole derivatives | ASAHI KASEI PHARMA CORPORATION (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8008506-B2 | Indazole compounds | ASAHI KASEI PHARMA CORPORATION (JP) | 2011-08-30 | — | — | US | disclosed |
| EP-2351742-A1 | INDAZOLE DERIVATIVE | Asahi Kasei Pharma Corporation (JP) | 2011-08-03 | — | — | EP | disclosed |
| EP-2345644-A1 | INDAZOLE COMPOUND | Asahi Kasei Pharma Corporation (JP) | 2011-07-20 | — | — | EP | disclosed |
| US-20100222404-A1 | INDAZOLE DERIVATIVE DIHYDROCHLORIDE | ASAHI KASEI PHARMA CORPORATION (JP) | 2010-09-02 | — | — | US | disclosed |
| US-20100160256-A1 | INDAZOLE COMPOUNDS | ASAHI KASEI PHARMA CORPORATION (JP) | 2010-06-24 | — | — | US | disclosed |
| US-20100152265-A1 | INDAZOLE DERIVATIVES | ASAHI KASEI PHARMA CORPORATION (JP) | 2010-06-17 | — | — | US | disclosed |
| US-7332622-B2 | Process for preparing optically active nitro compounds and cyano compounds | KANTO KAGUKU KABUSHIKI KAISHA (JP) | 2008-02-19 | — | — | US | disclosed |
| EP-1512678-A1 | Process for preparing optically active nitro compounds and cyano compounds | Kanto Kagaku Kabushiki Kaisha (JP) | 2005-03-09 | — | — | EP | disclosed |
| US-20040176616-A1 | Process for producing optically active compound | KANTO KAGAKU KABUSHIKI KAISHA | 2004-09-09 | — | — | US | disclosed |
| US-6696573-B1 | SYNTHESIS OF SUCH AS 2-(N-(2-(9H-CARBAZOL-2-YLOXY)ETHYL))-AMINO-1-((3 -METHYLSULFONYLAMINO)PHENYL)ETHANOL WITH ENHANCED OPTICAL PURITY | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2004-02-24 | — | — | US | disclosed |
| US-6686505-B2 | HYDROGENATION OF NITRO KETONE OR CYANO KETONE IN PRESENCE OF TRANSITION METAL COMPOUND CATALYST; AMINATION | KANTO KAGUKU KABUSHIKI KAISHA (JP) | 2004-02-03 | — | — | US | disclosed |
| US-20030225289-A1 | Process for the preparation of tricyclic amino alcohol derivatives | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2003-12-04 | — | — | US | disclosed |
| US-20030171592-A1 | Process for producing optically active amino alcohols and intermediates therefore | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 2003-09-11 | — | — | US | disclosed |
| EP-1308435-A2 | Process for producing optically active amino alcohols | Kanto Kagaku Kabushiki Kaisha (JP) | 2003-05-07 | — | — | EP | disclosed |
| EP-1209150-A1 | PROCESSES FOR THE PREPARATION OF TRICYCLIC AMINO ALCOHOL DERIVATIVES | Asahi Kasei Kabushiki Kaisha (JP) | 2002-05-29 | — | — | EP | disclosed |
| EP-1195371-A1 | PROCESS FOR THE PREPARATION OF TRICYCLIC AMINO ALCOHOL DERIVATIVES | Asahi Kasei Kabushiki Kaisha (JP) | 2002-04-10 | — | — | EP | disclosed |
| EP-1174426-A1 | METHOD FOR THE PREPARATION OF TRICYCLIC AMINO ALCOHOL DERIVATIVES THROUGH AZIDES | Asahi Kasei Kabushiki Kaisha (JP) | 2002-01-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030171592-A1 | Process for producing optically active amino alcohols and intermediates therefore | ADH1A, NOS1, ADH5 | NPSR1 1710/4885ALDH1A1 151/4885HTT 4114/4885 |
| US-20150152082-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE NAPHTHALENE COMPOUND | HRH1, HRH4, RB1 | NPSR1 595/4885ALDH1A1 343/4885HTT 3835/4885 |
| US-20100222404-A1 | INDAZOLE DERIVATIVE DIHYDROCHLORIDE | SFN, IDH3A, SRI | NPSR1 3494/4885ALDH1A1 2673/4885HTT 252/4885 |
| US-20030225289-A1 | Process for the preparation of tricyclic amino alcohol derivatives | ADH1A, ADH1C, OXER1 | NPSR1 755/4885ALDH1A1 80/4885HTT 2663/4885 |
| US-20100152265-A1 | INDAZOLE DERIVATIVES | ADRB3, INSR, ADRB1 | NPSR1 330/4885ALDH1A1 160/4885HTT 3141/4885 |
| US-20040176616-A1 | Process for producing optically active compound | OSTC, NPEPPS, PPOX | NPSR1 3017/4885ALDH1A1 3566/4885HTT 3491/4885 |
| US-20100160256-A1 | INDAZOLE COMPOUNDS | GPR119, ADRB1, ADRA1A | NPSR1 278/4885ALDH1A1 131/4885HTT 3085/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.