Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.52 |
| ▸ | GLI1 | P08151 | 1/20 | 0.50 |
| ▸ | GLI2 | P10070 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | CA12 | O43570 | 5/20 | 0.48 |
| ▸ | CA1 | P00915 | 5/20 | 0.48 |
| ▸ | CA2 | P00918 | 5/20 | 0.48 |
| ▸ | CA4 | P22748 | 5/20 | 0.48 |
| ▸ | CA9 | Q16790 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.47 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27547914 | 1.00 | PTGS1 (0.52) | PTGS1PTGS2GLI1GLI2MAPT | |
| SCHEMBL6332320 | 0.86 | GLI1 (0.53) | PTGS1PTGS2GLI1GLI2MAPT | |
| SCHEMBL27568086 | 0.86 | PTGS1 (0.49) | PTGS1PTGS2GLI1GLI2CA1 | |
| SCHEMBL7154919 | 0.86 | PTGS1 (0.49) | PTGS1PTGS2GLI1GLI2CA1 | |
| SCHEMBL12765415 | 0.82 | PTGS1 (0.55) | PTGS1PTGS2GLI1GLI2MAPT | |
| SCHEMBL1519474 | 0.82 | PTGS1 (0.50) | PTGS1PTGS2GLI1GLI2MAPT | |
| SCHEMBL3979139 | 0.81 | MAPT (0.53) | PTGS1PTGS2GLI1GLI2MAPT | |
| SCHEMBL7011092 | 0.81 | CA12 (0.57) | PTGS1PTGS2GLI1GLI2MAPT | |
| SCHEMBL6315710 | 0.81 | CA12 (0.57) | PTGS1PTGS2GLI1GLI2MAPT | |
| SCHEMBL6330554 | 0.81 | CXCR1 (0.55) | PTGS1PTGS2MAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030216392-A1 | N - ( 2 - aryl - propionyl ) - sulfonamides and pharmaceutical preparations containing them | DOMPE S.P.A. | 2003-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216392-A1 | N - ( 2 - aryl - propionyl ) - sulfonamides and pharmaceutical preparations containing them | ELANE, MPO, FPR1 | PTGS1 29/4885PTGS2 48/4885GLI1 3402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.