Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.67 |
| ▸ | MEN1 | O00255 | 7/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | LMNA | P02545 | 5/20 | 0.63 |
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | RAB9A | P51151 | 4/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | GFER | P55789 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | CCR6 | P51684 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7167224 | 0.93 | RAB9A (0.74) | KMT2AMEN1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL7165445 | 0.85 | ALDH1A1 (0.68) | KMT2AMEN1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL7166759 | 0.83 | RAB9A (0.60) | KMT2AMEN1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL7158954 | 0.83 | RAB9A (0.67) | KMT2AMEN1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL7161374 | 0.83 | ALDH1A1 (0.65) | KMT2AMEN1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL7662848 | 0.83 | RAB9A (0.81) | KMT2AMEN1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL7865724 | 0.82 | RAB9A (0.70) | KMT2AMEN1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL7157761 | 0.82 | RAB9A (0.60) | KMT2AMEN1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL7166733 | 0.81 | MEN1 (0.58) | KMT2AMEN1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL6819270 | 0.80 | KMT2A (0.65) | KMT2AMEN1SMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6555561-B2 | N-(5-((((5-Chloro-2,4-dimethoxyphenyl)amino)thioxomethyl)-amino)-2 -pyridinyl)-2-methylbenzamide, for example; inhibiting replication of a herpes virus | WYETH | 2003-04-29 | — | — | US | disclosed |