Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.70 |
| ▸ | NPC1 | O15118 | 3/20 | 0.70 |
| ▸ | POLB | P06746 | 3/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 7/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7162986 | 0.87 | NPC1 (0.53) | RAB9ANPC1POLBCYP2C9CYP2C19 | |
| SCHEMBL7167224 | 0.84 | RAB9A (0.74) | RAB9ANPC1POLBCYP2C9MEN1 | |
| SCHEMBL7159264 | 0.82 | KMT2A (0.67) | RAB9ANPC1POLBCYP2C9MEN1 | |
| SCHEMBL7157761 | 0.82 | RAB9A (0.60) | RAB9ANPC1POLBCYP2C9MEN1 | |
| SCHEMBL7165445 | 0.82 | ALDH1A1 (0.68) | RAB9ANPC1POLBCYP2C9MEN1 | |
| SCHEMBL7662848 | 0.80 | RAB9A (0.81) | RAB9ANPC1POLBCYP2C9MEN1 | |
| SCHEMBL6816807 | 0.78 | MAPT (0.56) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL6815098 | 0.77 | MAPT (0.61) | RAB9ANPC1CYP2C9CYP2C19MEN1 | |
| SCHEMBL6815108 | 0.76 | MAPT (0.67) | RAB9ANPC1CYP2C9CYP2C19MEN1 | |
| SCHEMBL7166733 | 0.76 | MEN1 (0.58) | RAB9ANPC1POLBCYP2C9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140913-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000034269-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |