SCHEMBL7159382

SCHEMBL7159382

O=C1OC(=O)c2cc(C(O)CCCCCO)ccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 2/20 0.38
HDAC8 Q9BY41 1/20 0.38
ALOX5 P09917 1/20 0.35
ALDH1A1 P00352 3/20 0.35
ADRB3 P13945 1/20 0.34
ALOX15 P16050 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
PNLIP P16233 2/20 0.33
PTGER2 P43116 1/20 0.33
LMNA P02545 2/20 0.32
HTT P42858 2/20 0.32
KDM4E B2RXH2 2/20 0.32
MEN1 O00255 1/20 0.32
RGS12 O14924 1/20 0.32
NPC1 O15118 1/20 0.32
PABPC1 P11940 1/20 0.32
RECQL P46063 1/20 0.32
RAB9A P51151 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28101847 0.94 ALDH1A1 (0.37) HDAC1HDAC8ALDH1A1ALOX15TDP1
SCHEMBL28789806 0.89 ALOX15 (0.38) HDAC1HDAC8ALDH1A1ALOX15TDP1
SCHEMBL10489405 0.83 BCL2 (0.42) HDAC1HDAC8ALOX5ALDH1A1ADRB3
SCHEMBL21177274 0.82 CYP3A4 (0.40) ALDH1A1ALOX15TDP1SMN1; SMN2IDO1
SCHEMBL9405094 0.75 ALOX15 (0.46) ALDH1A1ALOX15TDP1CA12CA1
SCHEMBL22017376 0.75 ALOX15 (0.46) ALDH1A1ALOX15TDP1MAPTCA12
Phthalic Anhydride SCHEMBL14991499 0.74 TDP1 (0.64) ALDH1A1ALOX15TDP1PNLIPLMNA
SCHEMBL20258532 0.73 MEN1 (0.38) ALDH1A1ALOX15TDP1MEN1KMT2A
SCHEMBL26728277 0.73 MEN1 (0.38) ALDH1A1ALOX15TDP1MEN1KMT2A
Phthalic Anhydride SCHEMBL11342944 0.72 TDP1 (0.67) ALDH1A1ALOX15TDP1LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116063885-B Composition and method for preparing polyurethane glove by using same 万华化学集团股份有限公司 2024-05-03 CN claimed
CN-117586659-A Antibacterial adherent surfaces 赢创加拿大公司 2024-02-23 CN claimed
CN-117447833-A Disposable polyurethane glove capable of efficiently and stably realizing industrial production and preparation process thereof 万华化学集团股份有限公司 2024-01-26 CN claimed
CN-111836847-B Carbonate-linked surface-modified macromolecules 赢创加拿大公司 2023-07-28 CN claimed
CN-116322811-A Surfaces with lubricating or low friction properties 赢创加拿大公司 2023-06-23 CN claimed
CN-116063885-A Composition and method for preparing polyurethane glove by using same 万华化学集团股份有限公司 2023-05-05 CN claimed
CN-115975576-A High-temperature-resistant polyurethane adhesive and preparation method thereof 有行鲨鱼(上海)科技股份有限公司 2023-04-18 CN claimed
CN-115895562-A Salt-fog-resistant single-component polyurethane hot melt adhesive and preparation method thereof 惠州市乐高新材料有限公司 2023-04-04 CN claimed
CN-115300672-A Vascular graft with modified surface 赢创加拿大公司 2022-11-08 CN claimed
CN-115300671-A Vascular graft with modified surface 赢创加拿大公司 2022-11-08 CN claimed
CN-110891621-B Vascular graft with modified surface 赢创加拿大公司 2022-07-08 CN claimed
CN-110891620-B Prosthetic valve with modified surface 赢创加拿大公司 2022-07-08 CN claimed
CN-110167995-B Plasticized PVC compounds having surface-modified macromolecules and articles made therefrom 界面生物公司 2022-07-01 CN claimed
CN-113980228-A Macromolecular surface modifier and synthetic method thereof 广州先进技术研究所 2022-01-28 CN claimed
CN-111836847-A Carbonate-linked surface-modified macromolecules 赢创加拿大公司 2020-10-27 CN claimed
CN-116063885-B Composition and method for preparing polyurethane glove by using same 万华化学集团股份有限公司 2024-05-03 CN disclosed
CN-117586659-A Antibacterial adherent surfaces 赢创加拿大公司 2024-02-23 CN disclosed
US-8900603-B2 Local delivery of drugs from self assembled coatings INTERFACE BIOLOGICS, INC. (CA) 2014-12-02 US disclosed
US-20130142834-A1 LOCAL DELIVERY OF DRUGS FROM SELF ASSEMBLED COATINGS Interface Biiologics, Inc. (CA) 2013-06-06 US disclosed
US-6635706-B1 Stable, precrosslinked urethane-acrylic hybrid polymer dispersion which produces films that dry rapidly at room temperature and are permanently crosslinked, and are resistant to abrasions, chemicals and stains REICHHOLD, INC. 2003-10-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130142834-A1 LOCAL DELIVERY OF DRUGS FROM SELF ASSEMBLED COATINGS OGFR, F13B, F7 HDAC1 2549/4885HDAC8 2354/4885ALOX5 2517/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.