Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 5/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.43 |
| ▸ | GABRE | P78334 | 1/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.43 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.43 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.43 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17199299 | 0.75 | ADORA3 (0.48) | — | |
| SCHEMBL17199197 | 0.75 | EPHX2 (0.51) | — | |
| SCHEMBL7154782 | 0.74 | GABRA2 (0.44) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL6974157 | 0.72 | GABRA2 (0.52) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL27477232 | 0.72 | GABRA2 (0.49) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL10701561 | 0.71 | GABRA2 (0.49) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL7483226 | 0.71 | GABRB3 (0.46) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL7713025 | 0.70 | GABRA2 (0.49) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL6975907 | 0.70 | GABRA2 (0.48) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL10701997 | 0.70 | GABRA2 (0.48) | GABRA2GABRB2GABRB3GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6545033-B1 | GABA receptor inhibitors | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2003-04-08 | — | — | US | disclosed |
| WO-2001025241-A2 | FUSED 1-(2,6-DICHLORO-4-TRIFLUOROMETHYLPHENYL)-PYRAZOLES, THE SYNTHESIS THEREOF AND THE USE THEREOF AS PESTICIDES | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2001-04-12 | — | — | WO | disclosed |