Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| P-Xylene SCHEMBL713870 | 0.83 | THRB (0.50) | THRBACHEHTTMAPTKMT2A | |
| SCHEMBL10624792 | 0.79 | MAPT (0.69) | THRBHTTCYP1A2CYP3A4CYP2D6 | |
| M-Xylene SCHEMBL10785138 | 0.75 | ACHE (0.75) | ACHEHTTCYP1A2CYP3A4CYP2D6 | |
| M-Xylene SCHEMBL11710232 | 0.74 | ACHE (0.57) | ACHEHTTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL23183178 | 0.73 | CTSL (0.41) | THRBHTTKMT2AMEN1 | |
| SCHEMBL12756951 | 0.73 | NPC1 (0.61) | CYP1A2CYP3A4CYP2D6MAPTKMT2A | |
| SCHEMBL11796808 | 0.73 | MAPT (0.59) | THRBHTTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11811489 | 0.73 | KMT2A (0.73) | HTTKMT2AALDH1A1PDE4APDE4B | |
| M-Xylene SCHEMBL28225217 | 0.73 | ACHE (0.71) | ACHEHTTCYP1A2CYP3A4CYP2D6 | |
| M-Xylene SCHEMBL11709090 | 0.73 | ACHE (0.71) | ACHEHTTCYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8354529-B2 | Polyamine derivative and polyol derivative | BASF SE (DE) | 2013-01-15 | — | — | US | disclosed |
| EP-2511274-A2 | Polyamine derivative | BASF SE (DE) | 2012-10-17 | — | — | EP | disclosed |
| EP-2484677-A1 | Polyamine derivative | BASF SE (DE) | 2012-08-08 | — | — | EP | disclosed |
| US-20120053270-A1 | POLYAMINE DERIVATIVE AND POLYOL DERIVATIVE | MITA NARUYOSHI (JP) | 2012-03-01 | — | — | US | disclosed |
| US-8076478-B2 | Stabilizer; photostability, heat resistance, ozone resistance, oxidation resistance, electromagnetic resistance | BASF SE (DE) | 2011-12-13 | — | — | US | disclosed |
| US-20080230743-A1 | Polyamine Derivative and Polyol Derivative | CIBA CORPORATION | 2008-09-25 | — | — | US | disclosed |
| EP-1840127-A1 | POLYAMINE DERIVATIVE AND POLYOL DERIVATIVE | Ciba Specialty Chemicals Holding Inc. (CH) | 2007-10-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053270-A1 | POLYAMINE DERIVATIVE AND POLYOL DERIVATIVE | H1-0, H1-3, NPM1 | THRB 2933/4885ACHE 3576/4885HTT 1457/4885 |
| US-20080230743-A1 | Polyamine Derivative and Polyol Derivative | H1-0, H1-3, H1-2 | THRB 2411/4885ACHE 4072/4885HTT 1001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.