Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 7/20 | 0.48 |
| ▸ | THRA | P10827 | 5/20 | 0.48 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7154880 | 1.00 | THRB (0.48) | THRBTHRAPPARAPPARGGPR84 | |
| SCHEMBL7063016 | 0.84 | ALOX5 (0.39) | THRBTHRAPPARAPPARGGPR35 | |
| SCHEMBL28827327 | 0.83 | THRB (0.51) | THRBTHRAGPR84PTGS2CYP3A4 | |
| SCHEMBL28061729 | 0.83 | THRB (0.51) | THRBTHRAGPR84PTGS2CYP3A4 | |
| SCHEMBL447954 | 0.81 | MAPT (0.46) | THRBGPR35 | |
| SCHEMBL10582524 | 0.77 | THRB (0.59) | THRBTHRAPPARAPPARGPTGS2 | |
| SCHEMBL4647837 | 0.77 | THRB (0.59) | THRBTHRAGPR84PTGS2 | |
| SCHEMBL4645645 | 0.77 | THRB (0.59) | THRBTHRAGPR84PTGS2 | |
| SCHEMBL3411706 | 0.77 | THRB (0.47) | THRBTHRAGPR84PTGS2CYP3A4 | |
| SCHEMBL7711136 | 0.76 | THRB (0.60) | THRBTHRAGPR84PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1109776-A1 | BROMINATED MATERIALS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2001-06-27 | — | — | EP | claimed |
| WO-2000014050-A1 | BROMINATED MATERIALS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2000-03-16 | — | — | WO | claimed |
| US-6533959-B2 | Formed from monomers such as 2-(4,6-dibromo-2-isopropyl phenoxy)ethyl acrylate; high index of refraction, useful to control flow and intensity of light | 3M INNOVATIVE PROPERTIES COMPANY | 2003-03-18 | — | — | US | disclosed |
| US-6359170-B1 | Brominated materials | 3M INNOVATIVE PROPERTIES COMPANY | 2002-03-19 | — | — | US | disclosed |