Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | THRA | P10827 | 5/20 | 0.38 |
| ▸ | THRB | P10828 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7160671 | 0.84 | THRB (0.48) | THRATHRBGPR35PPARGPPARA | |
| SCHEMBL7154880 | 0.84 | THRB (0.48) | THRATHRBGPR35PPARGPPARA | |
| SCHEMBL447954 | 0.83 | MAPT (0.46) | THRBLMNAMAPTKDM4EGPR35 | |
| SCHEMBL6514876 | 0.79 | THRB (0.54) | ALOX5THRATHRBPPARGPPARA | |
| SCHEMBL7708479 | 0.78 | TSHR (0.49) | ALOX5THRATHRBALDH1A1MEN1 | |
| SCHEMBL7067451 | 0.76 | GPR35 (0.42) | THRATHRBLMNAMAPTKDM4E | |
| SCHEMBL7065852 | 0.74 | GPR35 (0.40) | THRATHRBLMNAMAPTKDM4E | |
| SCHEMBL7702677 | 0.73 | THRB (0.44) | ALOX5THRATHRBALDH1A1MEN1 | |
| SCHEMBL7067194 | 0.73 | THRA (0.50) | ALOX5THRATHRBKDM4EGPR35 | |
| SCHEMBL7067841 | 0.73 | THRA (0.50) | ALOX5THRATHRBKDM4EGPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1109776-B1 | BROMINATED MATERIALS | MINNESOTA MINING & MFG (US) | 2003-06-04 | — | — | EP | claimed |
| EP-1109776-A1 | BROMINATED MATERIALS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2001-06-27 | — | — | EP | claimed |
| WO-2000014050-A1 | BROMINATED MATERIALS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2000-03-16 | — | — | WO | claimed |
| EP-1109776-B1 | BROMINATED MATERIALS | MINNESOTA MINING & MFG (US) | 2003-06-04 | — | — | EP | disclosed |
| US-6533959-B2 | Formed from monomers such as 2-(4,6-dibromo-2-isopropyl phenoxy)ethyl acrylate; high index of refraction, useful to control flow and intensity of light | 3M INNOVATIVE PROPERTIES COMPANY | 2003-03-18 | — | — | US | disclosed |
| US-6359170-B1 | Brominated materials | 3M INNOVATIVE PROPERTIES COMPANY | 2002-03-19 | — | — | US | disclosed |