Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | TPMT | P51580 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2489383 | 0.83 | APOBEC3A (0.62) | APOBEC3AAPOBEC3GACHE | |
| Iodide SCHEMBL6373433 | 0.79 | APOBEC3A (0.69) | APOBEC3AAPOBEC3GACHE | |
| Hydrochloric Acid SCHEMBL6368015 | 0.79 | APOBEC3A (0.59) | APOBEC3AAPOBEC3GACHE | |
| SCHEMBL2703780 | 0.73 | TPMT (0.41) | HDAC8TPMTAPPCA1CA2 | |
| SCHEMBL13567373 | 0.73 | APOBEC3A (0.53) | APOBEC3AAPOBEC3GACHE | |
| Ethane SCHEMBL27583817 | 0.71 | HDAC8 (0.47) | HDAC8TPMTAPPCA1CA2 | |
| SCHEMBL841700 | 0.71 | ACHE (0.53) | APOBEC3AAPOBEC3GACHECA1CA2 | |
| SCHEMBL10597056 | 0.71 | HDAC8 (0.50) | HDAC8TPMTAPPCA1CA2 | |
| SCHEMBL67142 | 0.71 | — | — | |
| SCHEMBL6299145 | 0.69 | APOBEC3A (0.42) | APOBEC3AAPOBEC3GACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066303-B1 | TRANSITION METAL COMPOUND CONTAINING CATIONIC GROUPS WHICH IS USED AS AN OLEFIN POLYMERIZATION CATALYST COMPONENT | BASELL POLYOLEFINE GMBH (DE) | 2003-09-10 | — | — | EP | claimed |
| US-6583238-B1 | Polypropylene having extraordinarily high stereospecificity and regiospecificity; | BASELL POLYOLEFINE GMBH (DE) | 2003-06-24 | — | — | US | claimed |
| US-6552210-B1 | Metallocenes which can be firmly fixed to support; gas phase polymerization | TARGOR GMBH (DE) | 2003-04-22 | — | — | US | claimed |
| EP-1066330-B1 | CATALYST SYSTEM, METHOD FOR THE PRODUCTION THEREOF, AND THE UTILIZATION THEREOF FOR THE POLYMERIZATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2002-02-06 | — | — | EP | claimed |
| US-6583238-B1 | Polypropylene having extraordinarily high stereospecificity and regiospecificity; | BASELL POLYOLEFINE GMBH (DE) | 2003-06-24 | — | — | US | disclosed |
| US-6552210-B1 | Metallocenes which can be firmly fixed to support; gas phase polymerization | TARGOR GMBH (DE) | 2003-04-22 | — | — | US | disclosed |