Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 5/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.59 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2489383 | 0.96 | APOBEC3A (0.62) | APOBEC3AAPOBEC3GACHECA12CA9 | |
| Iodide SCHEMBL6373433 | 0.92 | APOBEC3A (0.69) | APOBEC3AAPOBEC3GACHECA12CA9 | |
| Hydrochloric Acid SCHEMBL1508422 | 0.87 | ACHE (0.50) | APOBEC3AAPOBEC3GACHEALDH1A1TDP1 | |
| SCHEMBL13567373 | 0.85 | APOBEC3A (0.53) | APOBEC3AAPOBEC3GACHEALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL9711148 | 0.84 | ACHE (0.48) | APOBEC3AAPOBEC3GACHEKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL1231295 | 0.84 | MEN1 (0.47) | APOBEC3AAPOBEC3GACHEALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL28458738 | 0.82 | APOBEC3A (0.88) | APOBEC3AAPOBEC3GACHEKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL237898 | 0.82 | APOBEC3A (0.88) | APOBEC3AAPOBEC3GACHEKDM4EALDH1A1 | |
| SCHEMBL841700 | 0.82 | ACHE (0.53) | APOBEC3AAPOBEC3GACHEALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL11444627 | 0.82 | APOBEC3A (0.43) | APOBEC3AAPOBEC3GACHEKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050131192-A1 | Polymer and process for producing polymer | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2005-06-16 | — | — | US | disclosed |