Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7168095 | 0.80 | GABRA1 (0.35) | GAAKDM4EALDH1A1GABRA1GABRB2 | |
| SCHEMBL1235826 | 0.79 | MAPT (0.44) | MAPTGAAKDM4EALDH1A1GABRA1 | |
| SCHEMBL7165311 | 0.79 | ALDH1A1 (0.43) | MAPTGAAKDM4EALDH1A1GABRA1 | |
| SCHEMBL7165192 | 0.76 | ALDH1A1 (0.34) | MAPTGAAKDM4EALDH1A1GABRA1 | |
| SCHEMBL7158369 | 0.76 | TP53 (0.33) | GAA | |
| SCHEMBL1158926 | 0.75 | LIPG (0.40) | GABRA1GABRB2 | |
| SCHEMBL1159080 | 0.73 | CYP1A2 (0.39) | GAAKDM4EALDH1A1 | |
| SCHEMBL1159409 | 0.73 | TDP1 (0.37) | MAPTALDH1A1 | |
| SCHEMBL9003490 | 0.72 | GABRA1 (0.47) | MAPTGAAKDM4EALDH1A1GABRA1 | |
| SCHEMBL1158609 | 0.71 | MCHR1 (0.38) | MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811368-B1 | DENTAL PRIMER COMPOSITION AND POLYMERIZATION CATALYST | TOKUYAMA CORP (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-5866631-A | POLYMERIZABLE MONOMER CONTAINING AN ACIDIC GROUP, WATER, ARYL BORATE AND TRANSITION METAL COMPOUND. | TOKUYAMA CORPORATION (JP) | 1999-02-02 | — | — | US | disclosed |
| EP-0811368-A1 | DENTAL PRIMER COMPOSITION AND POLYMERIZATION CATALYST | TOKUYAMA CORPORATION (JP) | 1997-12-10 | — | — | EP | disclosed |