SCHEMBL7162245

SCHEMBL7162245

Cn1nc(-c2cc(O)c(C#N)cc2F)c(Br)c1C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.33
AR P10275 1/20 0.32
CYP11B2 P19099 1/20 0.32
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7164579 0.87 MEN1 (0.33) ARCYP11B2ESR1ESR2
SCHEMBL27814912 0.81 GAA (0.34) GAA
SCHEMBL8441031 0.78 AR (0.30) AR
SCHEMBL7967445 0.75 TRPV4 (0.37) CYP11B2
SCHEMBL8565002 0.73 GAA (0.37) GAA
SCHEMBL27814975 0.73 MEN1 (0.35) GAA
SCHEMBL8549829 0.73 GAA (0.37) GAA
SCHEMBL8441483 0.73 CYP11B1 (0.35) CYP11B2
SCHEMBL8444573 0.71 AR (0.36) AR
SCHEMBL14489535 0.71 PLAU (0.33) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6559102-B1 Applying one or more 3-aryl-pyrazole compounds to undesirable plants, fungi and/or their habitat BAYER AKTIENGESELLSCHAFT (DE) 2003-05-06 US disclosed
US-6495492-B1 HERBICIDES; DEFOLIANTS, DESICCANTS, HAULM KILLERS AND ESPECIALLY WEED KILLERS BAYER AKTIENGESELLSCHAFT (DE) 2002-12-17 US disclosed
EP-1107955-A2 SUBSTITUIERTE 3-ARYL-PYRAZOLE ALS HERBIZIDE Bayer Aktiengesellschaft (DE) 2001-06-20 EP disclosed
WO-2000012480-A2 SUBSTITUTED 3-ARYL-PYRAZOLES AS HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 2000-03-09 WO disclosed