Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.32 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8588979 | 0.84 | GABRG2 (0.38) | GAADPP4DPP7DPP8MAPT | |
| SCHEMBL8549829 | 0.77 | GAA (0.37) | GAAHSD11B1 | |
| SCHEMBL27814912 | 0.76 | GAA (0.34) | GAAHSD11B1 | |
| SCHEMBL8135469 | 0.74 | MAPT (0.34) | GAAMAPT | |
| SCHEMBL8566536 | 0.74 | PDE10A (0.33) | GAA | |
| SCHEMBL8569525 | 0.74 | MAPT (0.37) | GAAMAPTLMNA | |
| SCHEMBL7162245 | 0.73 | GAA (0.33) | GAA | |
| SCHEMBL3689455 | 0.72 | RORC (0.36) | GAA | |
| SCHEMBL14489535 | 0.72 | PLAU (0.33) | GAAMAPTLMNA | |
| SCHEMBL14039563 | 0.71 | ALDH1A1 (0.47) | MAPTNPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0553307-B1 | HERBICIDAL SUBSTITUTED ARYL-HALOALKYLPYRAZOLES | MONSANTO CO (US) | 1998-12-09 | — | — | EP | disclosed |
| EP-0846105-A1 | HERBICIDAL SUBSTITUTED 3-ARYL-PYRAZOLES | MONSANTO COMPANY (US) | 1998-06-10 | — | — | EP | disclosed |
| US-5675017-A | REACTING VINY ETHER DERIVATIVE WITH HYDRZINE OR SUBSTITUTED HYDRAZINE TO FORM A CHEMICAL INTERMEDIATE, REACTING INTERMEDIATE WITH SUBSTITUTED HALIDE OR DIALKYL SULFATE | MONSANTO COMPANY (US) | 1997-10-07 | — | — | US | disclosed |
| US-5672715-A | Herbicidal substituted 3-aryl-pyrazoles | MONSANTO COMPANY (US) | 1997-09-30 | — | — | US | disclosed |
| US-5668088-A | Herbicidal substituted 3-aryl-pyrazoles | MONSANTO COMPANY (US) | 1997-09-16 | — | — | US | disclosed |
| EP-0791571-A1 | Benzoyl derivatives | MONSANTO COMPANY (US) | 1997-08-27 | — | — | EP | disclosed |
| WO-1996040643-A1 | HERBICIDAL SUBSTITUTED 3-ARYL-PYRAZOLES | MONSANTO COMPANY (US) | 1996-12-19 | — | — | WO | disclosed |
| US-5536700-A | Herbicidal compositions comprising aryl-5-haloalkylpyrazoles and glyphosate, it's salts, diquat or paraquat | MONSANTO COMPANY (US) | 1996-07-16 | — | — | US | disclosed |
| US-5530126-A | ALKYLATION IN INERT SOLVENT | MONSANTO COMPANY (US) | 1996-06-25 | — | — | US | disclosed |
| US-5496956-A | BY ESTERIFICATION OF CARBOXY SUBSTITUTION WITH ALCOHOLS IN THE PRESENCE OF MINERAL ACID | MONSANTO COMPANY (US) | 1996-03-05 | — | — | US | disclosed |
| US-5489571-A | CROP-SAFE COMPOUNDS EFFECTIVE AT LOW CONCENTRATIONS | MONSANTO COMPANY (US) | 1996-02-06 | — | — | US | disclosed |
| CN-1030595-C | Substituted aryl-haloalkyl-pyrazoles as herbicides | MONSANTO CO (US) | 1996-01-03 | — | — | CN | disclosed |
| US-5281571-A | Herbicidal benzoxazinone- and benzothiazinone-substituted pyrazoles | MONSANTO COMPANY (US) | 1994-01-25 | — | — | US | disclosed |
| EP-0553307-A1 | HERBICIDAL SUBSTITUTED ARYL-HALOALKYLPYRAZOLES | MONSANTO COMPANY (US) | 1993-08-04 | — | — | EP | disclosed |
| WO-1992006962-A1 | HERBICIDAL SUBSTITUTED ARYL-HALOALKYLPYRAZOLES | MONSANTO COMPANY (US) | 1992-04-30 | — | — | WO | disclosed |