Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | P2RY2 | P41231 | 10/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 4/20 | 0.36 |
| ▸ | P2RY6 | Q15077 | 4/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.35 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.35 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.35 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.35 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.35 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7037107 | 0.95 | NT5E (0.44) | NT5EPOLBMEN1USP2KMT2A | |
| SCHEMBL7035782 | 0.91 | NT5E (0.41) | NT5EPOLBMEN1USP2KMT2A | |
| SCHEMBL7161171 | 0.90 | NT5E (0.43) | NT5EPOLBMEN1USP2KMT2A | |
| SCHEMBL7161805 | 0.88 | POLB (0.41) | NT5EPOLBMEN1USP2KMT2A | |
| SCHEMBL8427016 | 0.88 | NT5E (0.39) | NT5EPOLBMEN1USP2KMT2A | |
| SCHEMBL7162040 | 0.86 | RNASE1 (0.47) | NT5EPOLBMEN1USP2KMT2A | |
| SCHEMBL7162036 | 0.86 | MEN1 (0.38) | NT5EPOLBMEN1USP2KMT2A | |
| SCHEMBL8426931 | 0.85 | ALDH1A1 (0.38) | NT5EPOLBMEN1USP2KMT2A | |
| SCHEMBL15574462 | 0.84 | POLB (0.45) | NT5EPOLBMEN1USP2KMT2A | |
| SCHEMBL18879906 | 0.84 | POLB (0.45) | NT5EPOLBMEN1USP2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747389-B1 | 3'-SUBSTITUTED NUCLEOSIDE DERIVATIVES | TAIHO PHARMACEUTICAL CO LTD (JP) | 2003-09-10 | — | — | EP | disclosed |
| US-RE38090-E1 | Antitumor activity; useful for treatment and prevention of cancers | Matsuda, Akira (JP) | 2003-04-22 | — | — | US | disclosed |
| US-5763418-A | NUCLEOTIDE ANTITUMOR AGENTS | Matsuda, Akira (JP) | 1998-06-09 | — | — | US | disclosed |
| EP-0747389-A1 | 3'-SUBSTITUTED NUCLEOSIDE DERIVATIVES | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1996-12-11 | — | — | EP | disclosed |