Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1553413 | 0.81 | CES2 (0.47) | MAPTMEN1KMT2AALDH1A1CYP2C19 | |
| SCHEMBL2229589 | 0.80 | MAPT (0.41) | MAPTMEN1KMT2AKEAP1ALDH1A1 | |
| SCHEMBL7441502 | 0.78 | CES2 (0.50) | MEN1KMT2AALDH1A1GAAMAPK1 | |
| SCHEMBL11279860 | 0.77 | TRPA1 (0.36) | NR4A2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL8012738 | 0.76 | HDAC1 (0.60) | MAPTKMT2AKEAP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7450293 | 0.76 | CES2 (0.51) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL5839905 | 0.76 | HTR3E (0.39) | MAPTMEN1KMT2AALDH1A1CYP2C19 | |
| SCHEMBL2592 | 0.76 | CES2 (0.43) | MAPTALDH1A1SMN1; SMN2LMNATSHR | |
| SCHEMBL8010216 | 0.74 | CES1 (0.54) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL11784915 | 0.72 | MAPT (0.43) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0966454-B1 | DISUBSTITUTED BICYCLIC HETEROCYCLES, THEIR PRODUCTION AND USE AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-05-07 | — | — | EP | claimed |