Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.36 |
| ▸ | HTR2C | P28335 | 4/20 | 0.36 |
| ▸ | HTR2B | P41595 | 4/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | DRD4 | P21917 | 3/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17386884 | 0.81 | HTR2A (0.34) | HTR2AHTR6 | |
| SCHEMBL8157271 | 0.81 | HTR2A (0.34) | HTR2AHTR6 | |
| SCHEMBL8149561 | 0.80 | HTR6 (0.33) | HTR2AHTR6PRCP | |
| SCHEMBL7164209 | 0.73 | GAA (0.34) | HTR2ATP53TSHRALDH1A1CYP1A2 | |
| SCHEMBL2806909 | 0.71 | BRD4 (0.31) | HTR2AHTR6BRD4CCL2 | |
| SCHEMBL28646220 | 0.70 | — | — | |
| SCHEMBL8163025 | 0.68 | HTR6 (0.33) | HTR2AHTR6 | |
| SCHEMBL27874174 | 0.68 | HTR2A (0.33) | HTR2AHTR2CHTR2BSIGMAR1DRD2 | |
| Hydrochloric Acid SCHEMBL7781251 | 0.67 | HTR6 (0.32) | HTR2AHTR6 | |
| Bromide SCHEMBL6682824 | 0.67 | HTR2A (0.35) | HTR2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6388118-B1 | Process for the preparation of cyclopentadienyl compounds and compounds obtained therefrom | BASELL TECHNOLOGY COMPANY BV (NL) | 2002-05-14 | — | — | US | disclosed |
| EP-0722949-B1 | Process for the preparation of cyclopentadienyl compounds and compounds obtained therefrom | BASELL TECHNOLOGY CO BV (NL) | 2001-07-04 | — | — | EP | disclosed |
| US-6043403-A | Process for the preparation of cyclopentadienyl compounds and compounds obtained therefrom | MONTELL TECHNOLOGY COMPANY BV (NL) | 2000-03-28 | — | — | US | disclosed |
| EP-0722949-A2 | Process for the preparation of cyclopentadienyl compounds and compounds obtained therefrom | Montell Technology Company bv (NL) | 1996-07-24 | — | — | EP | disclosed |