Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 2/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6779045 | 0.86 | SMN1; SMN2 (0.43) | SMN1; SMN2TSHRMAPTL3MBTL1CYSLTR2 | |
| SCHEMBL7159095 | 0.86 | SMN1; SMN2 (0.43) | SMN1; SMN2TSHRMAPTATML3MBTL1 | |
| SCHEMBL7167893 | 0.82 | ALDH1A1 (0.37) | SMN1; SMN2TSHRMAPTL3MBTL1POLB | |
| Hydrochloric Acid SCHEMBL7167303 | 0.81 | NQO2 (0.48) | — | |
| SCHEMBL7164317 | 0.76 | SMN1; SMN2 (0.43) | SMN1; SMN2MAPTL3MBTL1POLBKMT2A | |
| SCHEMBL6779548 | 0.75 | SMN1; SMN2 (0.44) | SMN1; SMN2MAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL7161779 | 0.70 | L3MBTL1 (0.40) | SMN1; SMN2MAPTL3MBTL1PPARDPOLB | |
| SCHEMBL7163316 | 0.69 | SMN1; SMN2 (0.37) | SMN1; SMN2TSHRMAPTL3MBTL1POLB | |
| SCHEMBL7169154 | 0.69 | SMN1; SMN2 (0.37) | SMN1; SMN2TSHRMAPTATML3MBTL1 | |
| SCHEMBL6781801 | 0.69 | NQO2 (0.42) | SMN1; SMN2POLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0966454-B1 | DISUBSTITUTED BICYCLIC HETEROCYCLES, THEIR PRODUCTION AND USE AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-05-07 | — | — | EP | disclosed |