SCHEMBL716488

SCHEMBL716488

CCC(=O)c1cccc(C(F)(F)F)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.65
ALDH1A1 P00352 2/20 0.60
POLB P06746 1/20 0.60
TAS1R3 Q7RTX0 1/20 0.56
TAS1R1 Q7RTX1 1/20 0.56
ACHE P22303 1/20 0.56
NPSR1 Q6W5P4 1/20 0.55
HDAC3 O15379 1/20 0.55
HDAC1 Q13547 1/20 0.55
HDAC2 Q92769 1/20 0.55
SRD5A2 P31213 1/20 0.54
CTNNB1 P35222 1/20 0.54
WNT3A P56704 1/20 0.54
KMT2A Q03164 2/20 0.53
MEN1 O00255 1/20 0.53
P2RX1 P51575 1/20 0.51
LMNA P02545 1/20 0.51
NPC1 O15118 1/20 0.51
RAB9A P51151 1/20 0.51
TP53BP1 Q12888 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28098469 0.95 CES2 (0.59) CES2ALDH1A1POLBTAS1R3TAS1R1
SCHEMBL1746116 0.92 CES2 (0.56) CES2ALDH1A1POLBTAS1R3TAS1R1
SCHEMBL9468405 0.86 ALDH1A1 (0.61) CES2ALDH1A1POLBTAS1R3TAS1R1
SCHEMBL30758861 0.85 CES2 (0.69) CES2ALDH1A1POLBTAS1R3TAS1R1
SCHEMBL2073691 0.84 ACHE (0.72) CES2ALDH1A1POLBTAS1R3TAS1R1
SCHEMBL7218374 0.84 ACHE (0.72) CES2ALDH1A1POLBTAS1R3TAS1R1
SCHEMBL1712437 0.84 CES2 (0.67) CES2ALDH1A1POLBTAS1R3TAS1R1
SCHEMBL17134152 0.83 HDAC3 (0.60) CES2ALDH1A1POLBTAS1R3TAS1R1
SCHEMBL9536997 0.83 CES2 (0.61) CES2ALDH1A1POLBTAS1R3TAS1R1
SCHEMBL5167203 0.83 SMN1; SMN2 (0.60) ALDH1A1NPSR1HDAC3HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 265 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119684071-A Para-terphenyl derivative and synthesis method thereof 湖南大学 2025-03-25 CN claimed
CN-119433997-A Ultraviolet-resistant waterproof fabric for leisure cap 宿州先进服饰有限公司 2025-02-14 CN claimed
CN-119242206-A Electrolyte-resistant and high-temperature-resistant lithium battery termination adhesive tape 南京占一科技有限公司 2025-01-03 CN claimed
WO-2023102750-A1 FENFLURAMINE HAPTEN, AND PREPARATION METHOD THEREFOR AND USE THEREOF, FENFLURAMINE HAPTEN ARTIFICIAL ANTIGEN, AND FENFLURAMINE HAPTEN ANTIBODY 华南农业大学 2023-06-15 WO claimed
CN-114276264-B Fenfluramine hapten, artificial antigen, antibody, preparation method and application thereof 华南农业大学 2022-12-16 CN claimed
CN-114276264-A Fenfluramine hapten, artificial antigen, antibody, preparation method and application thereof 华南农业大学 2022-04-05 CN claimed
US-9201318-B2 Polymer for charge generation layer and charge transport layer formulation XEROX CORPORATION (US) 2015-12-01 US claimed
CN-105017012-A Acetoxylation method of benzyl groups UNIV JIANGXI NORMAL 2015-11-04 CN claimed
US-20150024310-A1 POLYMER FOR CHARGE GENERATION LAYER AND CHARGE TRANSPORT LAYER FORMULATION XEROX CORPORATION 2015-01-22 US claimed
US-8877413-B2 Flexible imaging members comprising improved ground strip XEROX CORPORATION (US) 2014-11-04 US claimed
US-20130052576-A1 FLEXIBLE IMAGING MEMBERS COMPRISING IMPROVED GROUND STRIP XEROX CORPORATION (US) 2013-02-28 US claimed
US-8343700-B2 Imaging members having stress/strain free layers XEROX CORPORATION (US) 2013-01-01 US claimed
US-8232030-B2 Curl-free imaging members with a slippery surface XEROX CORPORATION (US) 2012-07-31 US claimed
US-20110256474-A1 IMAGING MEMBERS HAVING STRESS/STRAIN FREE LAYERS XEROX CORPORATION (US) 2011-10-20 US claimed
US-20110229808-A1 CURL-FREE IMAGING MEMBERS WITH A SLIPPERY SURFACE XEROX CORPORATION (US) 2011-09-22 US claimed
US-20110136049-A1 IMAGING MEMBERS COMPRISING FLUOROKETONE XEROX CORPORATION (US) 2011-06-09 US claimed
CN-101318907-B Method for preparing benzoic-2-[[1-methyl-2-[3-(trifluoromethyl)-phenyl] ethyl] amido] ethyl ester hydrochlorate SHANDONG XINHUA PHARMACEUTICAL 2011-05-25 CN claimed
CN-101318907-A Method for preparing benzoic-2-[[1-methyl-2-[3-(trifluoromethyl)-phenyl] ethyl] amido] ethyl ester hydrochlorate SHANDONG XINHUA PHARMACEUTICAL (CN) 2008-12-10 CN claimed
CN-1126732-C Process for preparing benzoxy -2-[[1-methyl-2-[3-(trifluoromethyl)-phenyl]ethyl]amino] carbethoxy hydrochloride XINHUA PHARMACEUTICAL CO LTD S (CN) 2003-11-05 CN claimed
CN-1377876-A Process for preparing benzoxy -2-[[1-methyl-2-[3-(trifluoromethyl)-phenyl]ethyl]amino] carbethoxy hydrochloride XINHUA PHARMACEUTICAL CO LTD S (CN) 2002-11-06 CN claimed