Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 3/20 | 0.33 |
| ▸ | RARA | P10276 | 2/20 | 0.33 |
| ▸ | RARG | P13631 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4081296 | 0.85 | RARB (0.41) | ERN1RARBRARARARGKDM4E | |
| SCHEMBL5335699 | 0.81 | ERN1 (0.62) | ERN1CYP1A2KDM4EMEN1KMT2A | |
| SCHEMBL7166010 | 0.79 | BACE1 (0.34) | ERN1RARBRARARARGALDH1A1 | |
| SCHEMBL3966445 | 0.73 | ERN1 (0.33) | ERN1RARBRARARARG | |
| SCHEMBL10454858 | 0.72 | ERN1 (0.64) | ERN1CYP1A2KDM4EMEN1KMT2A | |
| SCHEMBL3043614 | 0.72 | SLC6A3 (0.41) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| Phosphine SCHEMBL28240146 | 0.70 | SLC6A3 (0.41) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL13004755 | 0.69 | MEN1 (0.43) | CYP1A2RARBRARARARGKDM4E | |
| SCHEMBL6852814 | 0.69 | HPRT1 (0.39) | CYP1A2KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL345587 | 0.69 | MEN1 (0.48) | RARBRARARARGKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1334107-A2 | NON-METALLOCENE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND USE OF THE SAME FOR THE POLYMERISATION OF OLEFINS | Basell Polyolefine GmbH (DE) | 2003-08-13 | — | — | EP | disclosed |
| WO-2002032908-A2 | NON-METALLOCENE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND USE OF THE SAME FOR THE POLYMERISATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2002-04-25 | — | — | WO | disclosed |