SCHEMBL345587

SCHEMBL345587

Oc1ccccc1C12CC3CC(CC(C3)C1)C2

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.48
KMT2A Q03164 5/20 0.48
POLB P06746 1/20 0.48
GAA P10253 1/20 0.48
GFER P55789 1/20 0.48
ALDH1A1 P00352 3/20 0.45
KDM4E B2RXH2 2/20 0.45
MAPT P10636 2/20 0.45
HPGD P15428 2/20 0.45
ALOX12 P18054 2/20 0.45
HSD17B10 Q99714 2/20 0.45
TSHR P16473 1/20 0.45
HTT P42858 1/20 0.45
ATM Q13315 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
RARB P10826 5/20 0.44
RARA P10276 3/20 0.44
RARG P13631 3/20 0.44
TP53 P04637 1/20 0.43
CYP3A4 P08684 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29809124 1.00 MEN1 (0.48) MEN1KMT2APOLBGAAGFER
SCHEMBL12804771 0.91 KDM4E (0.39) MEN1KMT2APOLBGAAGFER
SCHEMBL237723 0.88 GRIN2D (0.43) MEN1KMT2APOLBGAAGFER
SCHEMBL549642 0.84 MEN1 (0.46) MEN1KMT2APOLBGAAGFER
SCHEMBL3759976 0.84 MEN1 (0.46) MEN1KMT2APOLBGAAGFER
SCHEMBL3049402 0.83 ALOX5AP (0.37) MEN1KMT2APOLBGAAGFER
SCHEMBL27418461 0.81 MEN1 (0.43) MEN1KMT2APOLBGAAGFER
SCHEMBL13004755 0.81 MEN1 (0.43) MEN1KMT2APOLBGAAGFER
SCHEMBL548737 0.81 MEN1 (0.46) MEN1KMT2APOLBGAAGFER
SCHEMBL3752942 0.78 MEN1 (0.52) MEN1KMT2APOLBGAAGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114181091-B Synthesis process of adamantane triphenylamine 维思普新材料(苏州)有限公司 2024-06-14 CN claimed
CN-106220600-A Flavone derivatives and its production and use 厦门大学 2016-12-14 CN claimed
EP-1336597-B1 Hydroxyphenyl adamantanes and process for the production of the same HONSHU CHEMICAL IND (JP) 2008-07-16 EP claimed
US-20030187307-A1 Hydroxyphenyl adamantanes and process for the production of the same HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2003-10-02 US claimed
EP-1336597-A1 Hydroxyphenyl adamantanes and process for the production of the same Honshu Chemical Industry Co., Ltd. (JP) 2003-08-20 EP claimed
US-5851513-A Antiplaque oral composition and method COLGATE PALMOLIVE COMPANY (US) 1998-12-22 US claimed
CN-120192340-A Metal-containing film forming compound, metal-containing film forming composition, and pattern forming method 信越化学工业株式会社 2025-06-24 CN disclosed
CN-116694114-B Composition for forming metal oxide film, pattern forming method, and metal oxide film forming method 信越化学工业株式会社 2025-06-13 CN disclosed
CN-113050373-B Organic film forming material, organic film forming method, pattern forming method, and compound 信越化学工业株式会社 2025-05-16 CN disclosed
CN-113359390-B Composition for forming coated organic film, pattern forming method, polymer, and method for producing polymer 信越化学工业株式会社 2025-01-24 CN disclosed
CN-119087742-A Pattern forming method 信越化学工业株式会社 2024-12-06 CN disclosed
CN-118930452-A Organic film forming material, pattern forming method, and compound for organic film 信越化学工业株式会社 2024-11-12 CN disclosed
US-20240351965-A1 Synthesis and Evaluation of Novel (4-Hydroxyphenyl) Substituted Carbocycles as Potent and Selective Estrogen Receptor Beta Agonists CU Ventures, Inc. 2024-10-24 US disclosed
WO-2003020895-A2 METHOD OF DETERMINING THE NUCLEOTIDE SEQUENCE OF OLIGONUCLEOTIDES AND DNA MOLECULES ARIZONA BOARD OF REGENTS (US) 2003-03-13 WO disclosed
US-20020137062-A1 Method of determining the nucleotide sequence of oligonucleotides and DNA molecules HELICOS BIOSCIENCES CORPORATION 2002-09-26 US disclosed
EP-1082458-A1 METHOD OF DETERMINING THE NUCLEOTIDE SEQUENCE OF OLIGONUCLEOTIDES AND DNA MOLECULES ARIZONA BOARD OF REGENTS (US) 2001-03-14 EP disclosed
WO-1999057321-A9 METHOD OF DETERMINING THE NUCLEOTIDE SEQUENCE OF OLIGONUCLEOTIDES AND DNA MOLECULES UNIV ARIZONA (US) 2000-02-17 WO disclosed
WO-1999057321-A1 METHOD OF DETERMINING THE NUCLEOTIDE SEQUENCE OF OLIGONUCLEOTIDES AND DNA MOLECULES ARIZONA BOARD OF REGENTS (US) 1999-11-11 WO disclosed
CN-1117966-A Biphenyl derivatives EISAI CO LTD (JP) 1996-03-06 CN disclosed
US-3883603-A Adamantyl-(1)-{62 -naphthol KAO CORP 1975-05-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030187307-A1 Hydroxyphenyl adamantanes and process for the production of the same CYP8B1, DHPS, P4HA1 MEN1 1025/4885KMT2A 4019/4885POLB 727/4885
US-20240351965-A1 Synthesis and Evaluation of Novel (4-Hydroxyphenyl) Substituted Carbocycles as Potent and Selective Estrogen Receptor Beta Agonists ESR2, GPER1, ESR1 MEN1 4704/4885KMT2A 2068/4885POLB 1922/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.