Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 9/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | RARA | P10276 | 2/20 | 0.31 |
| ▸ | RARB | P10826 | 2/20 | 0.31 |
| ▸ | RARG | P13631 | 2/20 | 0.31 |
| ▸ | TLR2 | O60603 | 1/20 | 0.31 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.31 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4075387 | 0.85 | ERN1 (0.46) | ERN1ALDH1A1LMNARARARARB | |
| SCHEMBL7166007 | 0.83 | HDAC4 (0.43) | BACE1ERN1ALDH1A1LMNARARA | |
| SCHEMBL3962387 | 0.81 | ERN1 (0.50) | BACE1ERN1LMNAMTNR1AMTNR1B | |
| SCHEMBL7165307 | 0.79 | ERN1 (0.43) | BACE1ERN1ALDH1A1RARARARB | |
| SCHEMBL547455 | 0.73 | MEN1 (0.43) | ALDH1A1LMNARARARARBRARG | |
| SCHEMBL3965380 | 0.73 | ERN1 (0.44) | ERN1LMNATLR2TLR1TLR6 | |
| SCHEMBL9764115 | 0.72 | PTPN22 (0.44) | ALDH1A1RARARARBRARG | |
| SCHEMBL3043614 | 0.72 | SLC6A3 (0.41) | ALDH1A1LMNA | |
| Phosphine SCHEMBL28240146 | 0.70 | SLC6A3 (0.41) | ALDH1A1LMNA | |
| SCHEMBL7170981 | 0.70 | PPARG (0.40) | BACE1ERN1ALDH1A1TLR2TLR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1334107-A2 | NON-METALLOCENE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND USE OF THE SAME FOR THE POLYMERISATION OF OLEFINS | Basell Polyolefine GmbH (DE) | 2003-08-13 | — | — | EP | disclosed |
| WO-2002032908-A2 | NON-METALLOCENE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND USE OF THE SAME FOR THE POLYMERISATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2002-04-25 | — | — | WO | disclosed |