Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.53 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.50 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TPMT | P51580 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NNMT | P40261 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3628546 | 0.80 | GAA (0.42) | TSHRAPOBEC3AHTTAPOBEC3GALDH1A1 | |
| SCHEMBL21177391 | 0.79 | TSHR (0.47) | TSHRAPOBEC3AHTTAPOBEC3GNCOA1 | |
| SCHEMBL31336087 | 0.77 | HSD17B10 (0.56) | TSHRAPOBEC3AHTTAPOBEC3GNCOA1 | |
| SCHEMBL18786955 | 0.74 | CA2 (0.43) | TSHRAPOBEC3AHTTAPOBEC3GNCOA1 | |
| SCHEMBL30514835 | 0.74 | NCOA1 (0.42) | TSHRAPOBEC3AHTTAPOBEC3GNCOA1 | |
| SCHEMBL17403034 | 0.74 | ERN1 (0.39) | ALDH1A1HPGDMEN1KMT2ALMNA | |
| SCHEMBL5243855 | 0.74 | TSHR (0.53) | TSHRAPOBEC3AHTTAPOBEC3GNCOA1 | |
| SCHEMBL16689305 | 0.73 | PTPN1 (0.54) | TSHRAPOBEC3AHTTAPOBEC3GNCOA1 | |
| SCHEMBL22060757 | 0.73 | TSHR (0.49) | TSHRAPOBEC3AHTTAPOBEC3GNCOA1 | |
| SCHEMBL27968705 | 0.73 | ALDH1A1 (0.35) | NCOA1NCOA3ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6509334-B1 | This invention relates to compounds that antagonists of the progesterone receptor, their preparation and utility. Intracellular receptors (IR) form a class of structurally related gene regulators known as \"ligand dependent | AMERICAN HOME PRODUCTS CORPORATION | 2003-01-21 | — | — | US | disclosed |