Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 5/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7167447 | 0.89 | SMN1; SMN2 (0.47) | HTTHIF1AARLMNAHSD17B10 | |
| SCHEMBL7166226 | 0.88 | MAPT (0.48) | HTTHIF1AARLMNAHSD17B10 | |
| SCHEMBL7167448 | 0.87 | HTT (0.43) | HTTHIF1AARLMNAHSD17B10 | |
| SCHEMBL31098426 | 0.81 | RECQL (0.52) | HTTHIF1ARECQLARLMNA | |
| SCHEMBL2108251 | 0.80 | ALDH1A1 (0.44) | HTTHIF1AARLMNAMAPT | |
| SCHEMBL15677149 | 0.77 | AR (0.64) | HTTHIF1ARECQLARLMNA | |
| SCHEMBL14695225 | 0.76 | AR (0.67) | HTTHIF1AARLMNAHSD17B10 | |
| SCHEMBL14694822 | 0.76 | AR (0.67) | HTTHIF1AARLMNAHSD17B10 | |
| SCHEMBL14694972 | 0.76 | AR (0.67) | HTTHIF1AARLMNAHSD17B10 | |
| SCHEMBL4071969 | 0.73 | SMN1; SMN2 (0.49) | HTTHIF1AARLMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6566561-B1 | Phenoxy fluoro-alcohols, their preparation, and their use as phase modifiers and solvating agents | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF ENERGY | 2003-05-20 | — | — | US | disclosed |