Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MDH1 | P40925 | 2/20 | 0.44 |
| ▸ | MDH2 | P40926 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SHBG | P04278 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7167447 | 0.85 | SMN1; SMN2 (0.47) | SMN1; SMN2CYP3A4MDH1MDH2HTT | |
| SCHEMBL4071970 | 0.83 | LMNA (0.44) | HTTHIF1AARLMNAHSD17B10 | |
| SCHEMBL15677164 | 0.79 | AR (0.62) | SMN1; SMN2CYP3A4MDH1MDH2HTT | |
| SCHEMBL15677151 | 0.79 | SMN1; SMN2 (0.54) | SMN1; SMN2CYP3A4MDH1MDH2HTT | |
| SCHEMBL2108647 | 0.79 | SMN1; SMN2 (0.54) | SMN1; SMN2CYP3A4MDH1MDH2HTT | |
| SCHEMBL28000802 | 0.76 | CYP3A4 (0.61) | SMN1; SMN2CYP3A4MDH1MDH2HTT | |
| SCHEMBL7879426 | 0.76 | CYP3A4 (0.61) | SMN1; SMN2CYP3A4MDH1MDH2HTT | |
| SCHEMBL28001129 | 0.76 | CYP3A4 (0.61) | SMN1; SMN2CYP3A4MDH1MDH2HTT | |
| SCHEMBL10412598 | 0.75 | SMN1; SMN2 (0.60) | SMN1; SMN2CYP3A4MDH1MDH2HTT | |
| SCHEMBL13328787 | 0.74 | KDM4E (0.54) | SMN1; SMN2CYP3A4HTTHIF1ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6174503-B1 | NUCLEAR WASTES TREATMENT, ESPECIALLY WASTES WITH A HIGH CONCENTRATION OF COMPETING ALKALI METAL CATIONS | LOCKHEED MARTIN ENERGY RESEARCH CORPORATION | 2001-01-16 | — | — | US | claimed |
| CN-102935355-A | Adsorbent for separating heating element Cs and preparation method and application thereof | UNIV ZHEJIANG | 2013-02-20 | — | — | CN | disclosed |
| US-7524469-B2 | Extractant composition including crown ether and calixarene extractants | BATTELLE ENERGY ALLIANCE, LLC (US) | 2009-04-28 | — | — | US | disclosed |
| US-20080179568-A1 | EXTRACTANT COMPOSITION INCLUDING CROWN ETHER AND CALIXARENE EXTRACTANTS | ENERGY, UNITED STATES DEPARTMENT OF | 2008-07-31 | — | — | US | disclosed |
| US-7291316-B2 | Cesium and strontium extraction using a mixed extractant solvent including crown ether and calixarene extractants | BATTELLE ENERGY ALLIANCE, LLC (US) | 2007-11-06 | — | — | US | disclosed |
| US-20050211955-A1 | Cesium and strontium extraction using a mixed extractant solvent including crown ether and calixarene extractants | BATTELLE ENERGY ALLIANCE, LLC | 2005-09-29 | — | — | US | disclosed |
| US-6566561-B1 | Phenoxy fluoro-alcohols, their preparation, and their use as phase modifiers and solvating agents | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF ENERGY | 2003-05-20 | — | — | US | disclosed |
| US-6174503-B1 | NUCLEAR WASTES TREATMENT, ESPECIALLY WASTES WITH A HIGH CONCENTRATION OF COMPETING ALKALI METAL CATIONS | LOCKHEED MARTIN ENERGY RESEARCH CORPORATION | 2001-01-16 | — | — | US | disclosed |