Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 13/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7165673 | 0.87 | HTT (0.44) | HTTHIF1ALMNAHSD17B10AR | |
| SCHEMBL4071970 | 0.86 | LMNA (0.44) | HTTHIF1ALMNAHSD17B10PLA2G4B | |
| SCHEMBL7167447 | 0.84 | SMN1; SMN2 (0.47) | HTTHIF1ALMNAHSD17B10AR | |
| SCHEMBL7166226 | 0.83 | MAPT (0.48) | HTTHIF1ALMNAHSD17B10AR | |
| SCHEMBL2108648 | 0.79 | HTT (0.48) | HTTHIF1ALMNAHSD17B10PLA2G4B | |
| SCHEMBL7879429 | 0.77 | LMNA (0.47) | HTTHIF1ALMNAHSD17B10PLA2G4B | |
| SCHEMBL2108251 | 0.75 | ALDH1A1 (0.44) | HTTHIF1ALMNAARTDP1 | |
| SCHEMBL9636030 | 0.74 | MAPK1 (0.55) | HTTHIF1ALMNAHSD17B10AR | |
| SCHEMBL2108186 | 0.72 | CNR2 (0.49) | LMNAHSD17B10ARCNR2CNR1 | |
| SCHEMBL14695225 | 0.72 | AR (0.67) | HTTHIF1ALMNAHSD17B10AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6566561-B1 | Phenoxy fluoro-alcohols, their preparation, and their use as phase modifiers and solvating agents | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF ENERGY | 2003-05-20 | — | — | US | disclosed |