Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RARB | P10826 | 2/20 | 0.38 |
| ▸ | RARG | P13631 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | RARA | P10276 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13004790 | 0.81 | PTPN22 (0.46) | PTPN22LDHAALDH1A1MAPTKDM4E | |
| SCHEMBL548996 | 0.80 | MEN1 (0.48) | MEN1KMT2AALDH1A1MAPTRARB | |
| SCHEMBL3043614 | 0.79 | SLC6A3 (0.41) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL27714503 | 0.79 | MEN1 (0.40) | MEN1KMT2AALDH1A1MAPTRARB | |
| SCHEMBL8359113 | 0.78 | PTPN22 (0.37) | PTPN22LDHAALDH1A1MAPTKDM4E | |
| Phosphine SCHEMBL28240146 | 0.77 | SLC6A3 (0.41) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL548737 | 0.76 | MEN1 (0.46) | MEN1KMT2AALDH1A1MAPTRARB | |
| SCHEMBL13004762 | 0.76 | MEN1 (0.47) | MEN1KMT2AALDH1A1MAPTRARB | |
| SCHEMBL13004815 | 0.75 | NQO2 (0.46) | MEN1KMT2AALDH1A1MAPTRARB | |
| SCHEMBL3768061 | 0.73 | MEN1 (0.52) | MEN1KMT2AALDH1A1MAPTRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10175589-B2 | Quinone derivative and electrophotographic photosensitive member | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2019-01-08 | — | — | US | disclosed |
| US-20170363978-A1 | QUINONE DERIVATIVE AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2017-12-21 | — | — | US | disclosed |
| US-20170363978-A1 | QUINONE DERIVATIVE AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2017-12-21 | — | — | US | disclosed |
| US-20100316950-A1 | COMPOSITION FOR FORMING BASE FILM FOR LITHOGRAPHY AND METHOD FOR FORMING MULTILAYER RESIST PATTERN | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2010-12-16 | — | — | US | disclosed |
| US-20100316950-A1 | COMPOSITION FOR FORMING BASE FILM FOR LITHOGRAPHY AND METHOD FOR FORMING MULTILAYER RESIST PATTERN | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2010-12-16 | — | — | US | disclosed |
| US-5015758-A | Process for the preparation of 1-adamantane derivatives | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (CIRD) (FR) | 1991-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10175589-B2 | Quinone derivative and electrophotographic photosensitive member | KEAP1, NQO1, CBR3 | PTPN22 2368/4885LDHA 3052/4885MEN1 1482/4885 |
| US-20170363978-A1 | QUINONE DERIVATIVE AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | KEAP1, NQO1, CBR3 | PTPN22 2368/4885LDHA 3052/4885MEN1 1482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.