Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.58 |
| ▸ | CXCL8 | P10145 | 5/20 | 0.54 |
| ▸ | CLIC1 | O00299 | 1/20 | 0.54 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.48 |
| ▸ | TTR | P02766 | 2/20 | 0.48 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.48 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.48 |
| ▸ | ALB | P02768 | 1/20 | 0.48 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.48 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.48 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7161942 | 0.89 | PTGS2 (0.58) | PTGS2CXCL8CLIC1CLCN2CYP2C9 | |
| SCHEMBL7166064 | 0.87 | PTGS2 (0.62) | PTGS2CXCL8CLIC1CLCN2CYP2C9 | |
| SCHEMBL7166166 | 0.84 | CXCL8 (0.61) | PTGS2CXCL8CLIC1CLCN2CYP2C9 | |
| SCHEMBL7165384 | 0.80 | CXCL8 (0.58) | PTGS2CXCL8CLIC1CLCN2CYP2C9 | |
| SCHEMBL7166145 | 0.80 | PTGS2 (0.63) | PTGS2CXCL8CLIC1CLCN2CYP2C9 | |
| SCHEMBL7162207 | 0.80 | PTGS2 (0.56) | PTGS2CXCL8CLIC1CLCN2ALDH1A1 | |
| SCHEMBL7165032 | 0.79 | GRIK1 (0.56) | PTGS2CXCL8CLIC1CLCN2CYP2C9 | |
| SCHEMBL7166092 | 0.79 | PTGS2 (0.62) | PTGS2CXCL8CLIC1CLCN2CYP2C9 | |
| SCHEMBL7166047 | 0.79 | PTGS2 (0.61) | PTGS2CXCL8CLIC1CLCN2CYP2C9 | |
| SCHEMBL361662 | 0.77 | CXCL8 (0.67) | PTGS2CXCL8CLIC1CLCN2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6552077-B2 | Kidney disorders | EXOCELL, INC. | 2003-04-22 | — | — | US | disclosed |
| EP-1242069-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2002-09-25 | — | — | EP | disclosed |
| US-6355680-B1 | BLOCKING REACTION OF GLUCOSE AND ALBUMIN | EXOCELL, INC. | 2002-03-12 | — | — | US | disclosed |
| US-20010034359-A1 | Albumin-binding compounds that prevent nonenzymatic glycation and that may be used for treatment of glycation-related pathologies | EXOCELL, INC. | 2001-10-25 | — | — | US | disclosed |
| WO-2001003684-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2001-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010034359-A1 | Albumin-binding compounds that prevent nonenzymatic glycation and that may be used for treatment of glycation-related pathologies | ALB, AGER, TTR | PTGS2 2067/4885CXCL8 3032/4885CLIC1 3616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.