Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 5/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 2/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7171397 | 0.93 | CYP2D6 (0.44) | LPAR1CYP2D6CYP1A2PKMSMN1; SMN2 | |
| SCHEMBL5836130 | 0.80 | ALDH1A1 (0.50) | CYP2D6CYP1A2PKMSMN1; SMN2NPSR1 | |
| SCHEMBL28010633 | 0.79 | ALDH1A1 (0.40) | CYP2D6CYP1A2PKMSMN1; SMN2NPSR1 | |
| SCHEMBL10480811 | 0.79 | ALDH1A1 (0.48) | CYP2D6CYP1A2PKMSMN1; SMN2NPSR1 | |
| SCHEMBL9681180 | 0.78 | ALDH1A1 (0.46) | CYP2D6CYP1A2PKMSMN1; SMN2NPSR1 | |
| SCHEMBL27485932 | 0.75 | THRB (0.49) | CYP2D6CYP1A2PKMSMN1; SMN2NPSR1 | |
| SCHEMBL28191333 | 0.74 | MAPT (0.55) | CYP3A4TDP1TLR2ALDH1A1KMT2A | |
| SCHEMBL6909304 | 0.74 | ASAH1 (0.56) | LPAR1SMN1; SMN2TLR2ALDH1A1KMT2A | |
| SCHEMBL9680830 | 0.73 | CYP3A4 (0.48) | CYP2D6SMN1; SMN2CYP3A4CYP2C19CYP4F2 | |
| SCHEMBL28384042 | 0.73 | MAPT (0.58) | TLR2ALDH1A1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6657043-B1 | Free-radical polymerization initiators; polyalkoxyamines with phosphine derivative substituents | ATOFINA (FR) | 2003-12-02 | — | — | US | disclosed |