Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9680830 | 0.84 | CYP3A4 (0.48) | ALDH1A1CYP2D6SMN1; SMN2KMT2APOLB | |
| SCHEMBL9773219 | 0.83 | ALDH1A1 (0.47) | ALDH1A1TSHRHPGDTDP1L3MBTL1 | |
| SCHEMBL28081040 | 0.82 | ALDH1A1 (0.46) | ALDH1A1TSHRHPGDL3MBTL1P2RX4 | |
| SCHEMBL28081042 | 0.82 | ALDH1A1 (0.46) | ALDH1A1TSHRHPGDP2RX4CYP1A2 | |
| SCHEMBL7171397 | 0.80 | CYP2D6 (0.44) | ALDH1A1HPGDTDP1L3MBTL1CYP1A2 | |
| SCHEMBL9681177 | 0.79 | TSHR (0.46) | ALDH1A1TSHRTDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL7166503 | 0.78 | LPAR1 (0.44) | ALDH1A1HPGDTDP1CYP1A2CYP2D6 | |
| SCHEMBL11828483 | 0.77 | PTPN1 (0.46) | ALDH1A1HPGDL3MBTL1CYP2D6SMN1; SMN2 | |
| SCHEMBL6154764 | 0.76 | ALDH1A1 (0.41) | ALDH1A1TSHRHPGDKMT2APOLB | |
| SCHEMBL7407170 | 0.75 | ALDH1A1 (0.47) | ALDH1A1TSHRHPGDCYP2D6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0492078-A2 | Process for the preparation of butyle esters of 2-phenylecyclopropanecarboxylic acid | HÜLS AKTIENGESELLSCHAFT (DE) | 1992-07-01 | — | — | EP | disclosed |
| US-5118834-A | Decyclization of 5-phenylbutyrolactone in hydrochloric acid to give 4-chloro-4-phenylbutanoate; cyclization in sodium hydroxide | HUELS AKTIENGESELLSCHAFT (DE) | 1992-06-02 | — | — | US | disclosed |