Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 4/20 | 0.55 |
| ▸ | CA2 | P00918 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.53 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | PTPRB | P23467 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4643521 | 0.83 | LMNA (0.59) | CA1CA2MAPTTDP1CA12 | |
| SCHEMBL9917356 | 0.81 | LOXL2 (0.61) | LOXL2CA1CA2MAPTCYP4A11 | |
| SCHEMBL4640564 | 0.80 | ALDH1A1 (0.58) | MAPTTDP1MEN1KMT2ATSHR | |
| SCHEMBL850747 | 0.80 | LOXL2 (0.59) | LOXL2CA1CA2MAPTCYP4A11 | |
| SCHEMBL10661402 | 0.79 | LOXL2 (0.62) | LOXL2CA1CA2MAPTCYP4A11 | |
| SCHEMBL2241573 | 0.77 | LOXL2 (0.56) | LOXL2CA1CA2MAPTCYP4A11 | |
| SCHEMBL31185775 | 0.77 | LOXL2 (0.56) | LOXL2CA1CA2MAPTCYP4A11 | |
| SCHEMBL1598468 | 0.77 | ALDH1A1 (0.52) | MAPTTDP1MEN1KMT2ATSHR | |
| SCHEMBL9072931 | 0.77 | CA1 (0.60) | LOXL2CA1CA2MAPTCYP4A11 | |
| SCHEMBL25955548 | 0.77 | CA1 (0.50) | LOXL2CA1CA2MAPTCYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6566548-B1 | Alkylene- or phenylene- tetrabenzoic acids and derivatives | NIPPON SODA CO., LTD. (JP) | 2003-05-20 | — | — | US | disclosed |
| EP-1120391-A1 | MOLECULAR COMPOUNDS CONTAINING NOVEL CARBOXYLIC ACID DERIVATIVES AS THE CONSTITUENT COMPOUND | NIPPON SODA CO., LTD. (JP) | 2001-08-01 | — | — | EP | disclosed |