SCHEMBL7166606

SCHEMBL7166606

C=CCc1c(Br)c(Br)c2c(c1CC=C)Cc1ccccc1-2

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ADRA1D P25100 1/20 0.34
ADRA1A P35348 1/20 0.34
ADRA1B P35368 1/20 0.34
MAP3K9 P80192 1/20 0.33
MAP3K11 Q16584 1/20 0.33
PNMT P11086 1/20 0.33
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA4 P22748 1/20 0.30
CA6 P23280 1/20 0.30
MAOA P21397 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7166601 0.88 MAP3K9 (0.36) ADRA1DADRA1AADRA1BMAP3K9MAP3K11
SCHEMBL15048647 0.82 MAP3K9 (0.33) ADRA1DADRA1AADRA1BMAP3K9MAP3K11
SCHEMBL15048645 0.80 MAP3K9 (0.35) ADRA1DADRA1AADRA1BMAP3K9MAP3K11
SCHEMBL28282042 0.75 PNMT (0.41) ADRA1DADRA1AADRA1BPNMTCA1
SCHEMBL28591544 0.73 MAP3K9 (0.36) ADRA1DADRA1AADRA1BMAP3K9MAP3K11
SCHEMBL8622497 0.73 MAP3K9 (0.42) MAP3K9MAP3K11PNMTCA1CA2
SCHEMBL6677168 0.70 DRD2 (0.36) MAP3K9MAP3K11
SCHEMBL1656576 0.70 DRD2 (0.36) MAP3K9MAP3K11
SCHEMBL300453 0.70 PNMT (0.45) ADRA1DADRA1AADRA1BMAP3K9MAP3K11
SCHEMBL9578161 0.69 PNMT (0.44) ADRA1DADRA1AADRA1BPNMTCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6555682-B1 S-triazines substituted by 1,3,5-tri(7-benzothiazol-2-yl or 7-diphenylamino fluoren-2-yl dericatives; absorption cross-sections; lasers; fluorescent dyes THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE 2003-04-29 US disclosed