Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 12/20 | 0.37 |
| ▸ | NPY1R | P25929 | 7/20 | 0.37 |
| ▸ | AVPR1B | P47901 | 4/20 | 0.36 |
| ▸ | NPY2R | P49146 | 5/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7170495 | 0.88 | NPY4R (0.38) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL7167389 | 0.86 | AVPR1B (0.35) | NPY4RNPY1RAVPR1BNPY2RNPY5R | |
| SCHEMBL7170368 | 0.80 | NPY4R (0.42) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL8064263 | 0.76 | AVPR1B (0.40) | NPY4RNPY1RAVPR1BAVPR1AF2 | |
| SCHEMBL7170382 | 0.75 | PLG (0.35) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL7170054 | 0.75 | PLG (0.35) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL7168920 | 0.75 | NPY4R (0.35) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL7171393 | 0.75 | AVPR1B (0.46) | NPY4RNPY1RAVPR1BNPY2RNPY5R | |
| SCHEMBL28860152 | 0.74 | AVPR1B (0.39) | AVPR1BAVPR1AF2 | |
| SCHEMBL28860154 | 0.74 | AVPR1B (0.39) | AVPR1BAVPR1AF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0789578-B1 | MULTICATALYTIC PROTEASE INHIBITORS | CEPHALON INC (US) | 2003-06-04 | — | — | EP | disclosed |
| EP-0789578-A4 | MULTICATALYTIC PROTEASE INHIBITORS | CEPHALON INC (US) | 2000-09-20 | — | — | EP | disclosed |
| EP-0789578-A1 | MULTICATALYTIC PROTEASE INHIBITORS | CEPHALON, INC. (US) | 1997-08-20 | — | — | EP | disclosed |
| WO-1996014857-A1 | MULTICATALYTIC PROTEASE INHIBITORS | CEPHALON, INC. (US) | 1996-05-23 | — | — | WO | disclosed |