Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7425654 | 0.84 | TSHR (0.35) | MMP1MMP2MMP3ALDH1A1 | |
| SCHEMBL15257417 | 0.82 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL2714777 | 0.81 | MMP1 (0.34) | MMP1MMP2MMP3ALDH1A1 | |
| SCHEMBL779433 | 0.81 | TRPM8 (0.45) | — | |
| SCHEMBL3090613 | 0.80 | METAP1 (0.36) | PPARD | |
| SCHEMBL4158403 | 0.79 | PPARD (0.39) | MMP1MMP2MMP3ALDH1A1PPARD | |
| SCHEMBL11174466 | 0.79 | ALDH1A1 (0.38) | MMP1MMP2MMP3ALDH1A1 | |
| SCHEMBL1376856 | 0.79 | PPARD (0.52) | MMP1MMP2MMP3PPARD | |
| SCHEMBL10799957 | 0.78 | LPAR3 (0.50) | — | |
| SCHEMBL2150294 | 0.78 | LPAR3 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6534489-B1 | Organophosphorus compounds and the use thereof | JOMAA PHARMAKA GMBH (DE) | 2003-03-18 | — | — | US | disclosed |