Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11647775 | 0.83 | DDB1 (0.56) | ALDH1A1MAPTLMNAGAADDB1 | |
| SCHEMBL7167696 | 0.82 | ALDH1A1 (0.67) | ALDH1A1MAPTLMNATDP1GAA | |
| SCHEMBL11649762 | 0.79 | TDP1 (0.45) | ALDH1A1MAPTLMNATDP1GAA | |
| SCHEMBL9336803 | 0.79 | KMT2A (0.60) | ALDH1A1MAPTLMNATDP1GAA | |
| SCHEMBL8354029 | 0.75 | GAA (0.58) | ALDH1A1MAPTTDP1GAAMEN1 | |
| SCHEMBL11650712 | 0.72 | LMNA (0.56) | ALDH1A1MAPTLMNAGAAKDM4E | |
| SCHEMBL11653846 | 0.72 | ALOX15 (0.59) | ALDH1A1MAPTLMNAKDM4EDDB1 | |
| SCHEMBL13527924 | 0.72 | TDP1 (0.80) | ALDH1A1MAPTLMNATDP1GAA | |
| SCHEMBL11648008 | 0.72 | TDP1 (0.52) | ALDH1A1MAPTLMNATDP1GAA | |
| SCHEMBL10737695 | 0.71 | GAA (0.48) | ALDH1A1MAPTLMNATDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4094741-A | CULTURES, ASYMMETRIC HYDROLYSIS | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JA) | 1978-06-13 | — | — | US | disclosed |