SCHEMBL7167997

SCHEMBL7167997

Cc1c(F)c(F)cc(I)c1F

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL169896 0.80 CA1 (0.38) RAPGEF4
SCHEMBL18428488 0.79 HDAC1 (0.31)
SCHEMBL28313985 0.79 RAPGEF4 (0.30) RAPGEF4
SCHEMBL26548110 0.77
SCHEMBL24899658 0.75 TPMT (0.34)
SCHEMBL2935059 0.75 CES2 (0.32)
Methyl Alcohol SCHEMBL9652269 0.75 CA1 (0.40) RAPGEF4
SCHEMBL2209559 0.74 RAPGEF4 (0.39) RAPGEF4
SCHEMBL18721405 0.74 HDAC1 (0.31)
SCHEMBL19822782 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6563005-B1 Reacting aryl compound with phosphine in presence of Group VIII metal catalyst CYTEC TECHNOLOGY CORP. 2003-05-13 US disclosed