Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28298864 | 0.80 | ACHE (0.36) | ACHETUBB1 | |
| SCHEMBL135396 | 0.78 | TUBB1 (0.32) | TPMTMCL1ACHETUBB1 | |
| SCHEMBL31210105 | 0.78 | TUBB1 (0.32) | TPMTMCL1ACHETUBB1 | |
| SCHEMBL27628106 | 0.75 | CA2 (0.43) | TPMTACHETUBB1 | |
| SCHEMBL7167997 | 0.75 | RAPGEF4 (0.30) | — | |
| SCHEMBL28940453 | 0.74 | GRIN2D (0.33) | TPMTMCL1ACHETUBB1 | |
| SCHEMBL24899657 | 0.72 | KDM4E (0.31) | MCL1TUBB1 | |
| SCHEMBL16256381 | 0.71 | ACHE (0.36) | ACHETUBB1 | |
| SCHEMBL7131189 | 0.71 | ACHE (0.46) | TPMTMCL1ACHE | |
| SCHEMBL28313985 | 0.70 | RAPGEF4 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023284869-A1 | SULFUR/PHOSPHORUS-CONTAINING ARYL COMPOUND AND APPLICATION THEREOF | 南京明德新药研发有限公司 | 2023-01-19 | — | — | WO | disclosed |