Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | FFAR2 | O15552 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2423106 | 0.84 | FFAR2 (0.64) | KMT2AFFAR2L3MBTL1MEN1 | |
| SCHEMBL17915487 | 0.81 | KMT2A (0.78) | KMT2ASLC6A3MEN1 | |
| SCHEMBL1154849 | 0.78 | L3MBTL1 (0.49) | KMT2AFFAR2L3MBTL1SLC6A2SLC6A4 | |
| SCHEMBL4064082 | 0.77 | ALDH1A1 (0.56) | KMT2AFFAR2L3MBTL1SLC6A2SLC6A4 | |
| SCHEMBL18547195 | 0.77 | HDAC4 (0.57) | KMT2AFFAR2L3MBTL1SLC6A2SLC6A4 | |
| SCHEMBL1978245 | 0.77 | HDAC4 (0.57) | KMT2AFFAR2L3MBTL1SLC6A2SLC6A4 | |
| SCHEMBL22491773 | 0.77 | FFAR2 (0.47) | KMT2AFFAR2L3MBTL1SLC6A2SLC6A4 | |
| SCHEMBL1155156 | 0.76 | L3MBTL1 (0.50) | KMT2AFFAR2L3MBTL1SLC6A2SLC6A4 | |
| SCHEMBL21787636 | 0.76 | L3MBTL1 (0.50) | KMT2AFFAR2L3MBTL1SLC6A2SLC6A4 | |
| SCHEMBL4507146 | 0.76 | L3MBTL1 (0.50) | KMT2AFFAR2L3MBTL1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6566547-B1 | 3-alkoxy-2-phenylacrylic acid derivatives | ZENECA LIMITED (GB) | 2003-05-20 | — | — | US | disclosed |
| US-5315025-A | Acrylate ethers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-05-24 | — | — | US | disclosed |
| EP-0178826-B1 | FUNGICIDES | ZENECA LIMITED (GB) | 1991-12-18 | — | — | EP | disclosed |
| EP-0431328-A2 | Fungicides | ZENECA LIMITED (GB) | 1991-06-12 | — | — | EP | disclosed |
| EP-0178826-A2 | Fungicides | ZENECA LIMITED (GB) | 1986-04-23 | — | — | EP | disclosed |