SCHEMBL716839

SCHEMBL716839

O=S(=O)(c1ccccc1F)c1ccc(Cl)cc1Cl

nearest known ligand 0.54

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 13/20 0.54
CNR2 P34972 13/20 0.51
CYP2C9 P11712 6/20 0.47
HSD11B1 P28845 1/20 0.44
AKR1B1 P15121 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13343182 0.87 CNR1 (0.58) CNR1CNR2CYP2C9
SCHEMBL6335085 0.83 AKR1B1 (0.56) HSD11B1AKR1B1
SCHEMBL29058000 0.83 CNR1 (0.41) CNR1CNR2CYP2C9HSD11B1AKR1B1
Hydrochloric Acid SCHEMBL11256201 0.81 AKR1B1 (0.54) HSD11B1AKR1B1
SCHEMBL2124755 0.79 AKR1B1 (0.53) CNR1CNR2HSD11B1AKR1B1
SCHEMBL30333632 0.79 AKR1B1 (0.53) CNR1CNR2HSD11B1AKR1B1
SCHEMBL250919 0.79 AKR1B1 (0.53) CNR1CNR2HSD11B1AKR1B1
SCHEMBL29058033 0.77 PSEN1 (0.41) CNR1CNR2CYP2C9HSD11B1AKR1B1
SCHEMBL1466470 0.77 TDP1 (0.50) CNR2HSD11B1AKR1B1
SCHEMBL3446333 0.77 CNR1 (0.58) CNR1CNR2CYP2C9HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2206547-B1 NITROGEN-CONTAINING AROMATIC COMPOUNDS AND PROCESSES FOR THE PRODUCTION OF THE SAME, POLYMERS AND PROTON CONDUCTIVE MEMBRANES OF THESE COMPOUNDS JSR CORP (JP) 2016-03-16 EP disclosed
US-8309678-B2 Aromatic compound and polyarylene copolymer having nitrogen-containing heterocycle including sulfonic acid group in side chain JSR CORPORATION (JP) 2012-11-13 US disclosed
US-20120052412-A1 POLYARYLENE BLOCK COPOLYMER HAVING SULFONIC ACID GROUP AND USE THEREOF HONDA MOTOR CO., LTD. (JP) 2012-03-01 US disclosed
US-7906608-B2 Nitrogenated aromatic compound, process for production of the same, polymer, and proton conductive membrane JSR CORPORATION (JP) 2011-03-15 US disclosed
EP-2206547-A1 Nitrogen-containing aromatic compounds and processes for the production of the same, polymers and proton conductive membranes of these compounds JSR Corporation (JP) 2010-07-14 EP disclosed
US-20100152308-A1 NOVEL AROMATIC COMPOUND AND POLYARYLENE COPOLYMER HAVING NITROGEN-CONTAINING HETEROCYCLE INCLUDING SULFONIC ACID GROUP IN SIDE CHAIN JSR CORPORATION (JP) 2010-06-17 US disclosed
EP-2154173-A1 NOVEL AROMATIC COMPOUND, AND POLYARYLENE COPOLYMER HAVING NITROGEN-CONTAINING HETEROCYCLIC RING CONTAINING SULFONIC ACID GROUP IN SIDE CHAIN JSR Corporation (JP) 2010-02-17 EP disclosed
US-7658867-B2 Includes anode electrode, cathode electrode, and proton conductive membrane, anode electrode and cathode electrode being disposed on opposite sides of the proton conductive membrane, in which proton conductive membrane includes polyarylene with CO or so2 linkages; workability; superior power generation HONDA MOTOR CO., LTD. (JP) 2010-02-09 US disclosed
US-20090149623-A1 NITROGENATED AROMATIC COMPOUND, PROCESS FOR PRODUCTION OF THE SAME, POLYMER, AND PROTON CONDUCTIVE MEMBRANE JSR CORPORATION (JP) 2009-06-11 US disclosed
EP-1905791-A1 NITROGENATED AROMATIC COMPOUND, PROCESS FOR PRODUCTION OF THE SAME, POLYMER, AND PROTON CONDUCTIVE MEMBRANE JSR Corporation (JP) 2008-04-02 EP disclosed
US-20070015024-A1 Membrane-electrode assembly for solid polymer electrolyte fuel cell HONDA MOTOR CO., LTD. 2007-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100152308-A1 NOVEL AROMATIC COMPOUND AND POLYARYLENE COPOLYMER HAVING NITROGEN-CONTAINING HETEROCYCLE INCLUDING SULFONIC ACID GROUP IN SIDE CHAIN SCO2, H1-0, H1-10 CNR1 551/4885CNR2 289/4885CYP2C9 2313/4885
US-20090149623-A1 NITROGENATED AROMATIC COMPOUND, PROCESS FOR PRODUCTION OF THE SAME, POLYMER, AND PROTON CONDUCTIVE MEMBRANE SCO2, KCNH2, KCNH3 CNR1 388/4885CNR2 278/4885CYP2C9 1118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.