Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.45 |
| ▸ | HTR3B | O95264 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.45 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5635573 | 0.91 | NOTUM (0.53) | NOTUMTSHRRAB9AL3MBTL1HTR3E | |
| SCHEMBL600415 | 0.89 | NOTUM (0.61) | NOTUMTSHRRAB9AL3MBTL1HTR3E | |
| SCHEMBL30109103 | 0.89 | NOTUM (0.61) | NOTUMTSHRRAB9AL3MBTL1HTR3E | |
| Hydrochloric Acid SCHEMBL7492690 | 0.86 | NOTUM (0.57) | NOTUMTSHRRAB9AL3MBTL1HTR3E | |
| Hydrochloric Acid SCHEMBL7492685 | 0.86 | NOTUM (0.57) | NOTUMTSHRRAB9AL3MBTL1HTR3E | |
| SCHEMBL30546903 | 0.82 | NOTUM (0.49) | NOTUMTSHRRAB9AL3MBTL1HTR3E | |
| SCHEMBL7162470 | 0.82 | RAB9A (0.50) | NOTUMTSHRRAB9AL3MBTL1HTR3E | |
| SCHEMBL25433608 | 0.81 | NOTUM (0.49) | NOTUMTSHRRAB9AL3MBTL1HTR3E | |
| SCHEMBL28587036 | 0.81 | NOTUM (0.47) | NOTUMTSHRRAB9AL3MBTL1HTR3E | |
| SCHEMBL30488374 | 0.79 | NOTUM (0.47) | NOTUMTSHRRAB9AL3MBTL1HTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002540192-A | — | — | 2002-11-26 | — | — | JP | claimed |
| EP-1165511-A2 | METHOD OF PRODUCING HETEROCYCLIC CARBAMATES FROM AZA-HETEROCYCLIC COMPOUNDS AND CARBON DIOXIDE | GÖDECKE GMBH (DE) | 2002-01-02 | — | — | EP | claimed |
| WO-2000058286-A2 | METHOD OF PRODUCING HETEROCYCLIC CARBAMATES FROM AZA-HETEROCYCLIC COMPOUNDS AND CARBON DIOXIDE | Gödecke GmbH (DE) | 2000-10-05 | — | — | WO | claimed |
| US-6566533-B1 | Reacting aza-heterocyclic compounds (indoles and carbazoles) with alkyl- or aryl-halides in the presence of carbon dioxide and alkali carbonate | WARNER-LAMBERT COMPANY LLC | 2003-05-20 | — | — | US | disclosed |
| EP-1165511-A2 | METHOD OF PRODUCING HETEROCYCLIC CARBAMATES FROM AZA-HETEROCYCLIC COMPOUNDS AND CARBON DIOXIDE | GÖDECKE GMBH (DE) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000058286-A2 | METHOD OF PRODUCING HETEROCYCLIC CARBAMATES FROM AZA-HETEROCYCLIC COMPOUNDS AND CARBON DIOXIDE | Gödecke GmbH (DE) | 2000-10-05 | — | — | WO | disclosed |