Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 3/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7169135 | 0.89 | TSHR (0.46) | TSHRHSD17B10KDM4EALDH1A1CDC25B | |
| SCHEMBL4984915 | 0.87 | TSHR (0.50) | TSHRHSD17B10KDM4EALDH1A1CYP3A4 | |
| SCHEMBL6677331 | 0.83 | PPIA (0.51) | TSHRALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL12417943 | 0.80 | TSHR (0.62) | TSHRHSD17B10KDM4EALDH1A1CYP3A4 | |
| SCHEMBL4987083 | 0.79 | CA12 (0.54) | TSHRHSD17B10KDM4EALDH1A1CYP3A4 | |
| SCHEMBL16401931 | 0.78 | HSD17B10 (0.60) | TSHRHSD17B10KDM4EALDH1A1CYP3A4 | |
| SCHEMBL2422146 | 0.74 | KDM4E (0.48) | TSHRHSD17B10KDM4EALDH1A1CYP3A4 | |
| SCHEMBL9528504 | 0.72 | CNR1 (0.41) | KDM4EALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL28399309 | 0.72 | SGMS2 (0.47) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL1425344 | 0.72 | NUDT1 (0.47) | TSHRHSD17B10KDM4EALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6569894-B1 | Such as N-(3-(2-(4-phenylbutyl)-2,3-dihydrobenzofuran-4-yl)propyl)acetamide for treating circadian rhythm-related disorders | BRISTOL-MYERS SQUIBB COMPANY | 2003-05-27 | — | — | US | disclosed |